Swiss TPH

Adams M, Plitzko I, Kaiser M, Brun R & Hamburger M (2009) HPLC-profiling for antiplasmodial compounds-3-methoxycarpachromene from Pistacia atlantica. Planta Medica 75, 948.

Adams M, Zimmermann S, Kaiser M, Brun R & Hamburger M (2009) A protocol for HPLC-based activity profiling for natural products with activities against tropical parasites. Nat Prod Commun 4, 1377-1381. PM:19911575

Alp M, Göker H, Brun R & Yildiz S (2009) Synthesis and antiparasitic and antifungal evaluation of 2'-arylsubstituted-1H,1'H-[2,5']bisbenzimidazolyl-5-carboxamidines. Eur J Med Chem 44, 2002-2008. PM:19010569

Bakunov SA, Bakunova SM, Bridges AS, Wenzler T, Barszcz T, Werbovetz KA, Brun R & Tidwell RR (2009) Synthesis and antiprotozoal properties of pentamidine congeners bearing the benzofuran motif. J Med Chem 52, 5763-5767. PM:19757840

Bakunova SM, Bakunov SA, Patrick DA, Kumar EV, Ohemeng KA, Bridges AS, Wenzler T, Barszcz T, Jones SK, Werbovetz KA, Brun R & Tidwell RR (2009) Structure-activity study of pentamidine analogues as antiprotozoal agents. J Med Chem 52, 2016-2035. PM:19267462

Bakunova SM, Bakunov SA, Wenzler T, Barszcz T, Werbovetz KA, Brun R & Tidwell RR (2009) Synthesis and antiprotozoal activity of pyridyl analogues of pentamidine. J Med Chem 52, 4657-4667. PM:19606902

Baliani A, Peal V, Gros L, Brun R, Kaiser M, Barrett MP & Gilbert IH (2009) Novel functionalized melamine-based nitroheterocycles: synthesis and activity against trypanosomatid parasites. Org Biomol Chem 7, 1154-1166. PM:19262935

Balmer O & Ebert D (2009) Medizin: Evolution wird (be)greifbar. Uni Nova 111, 26-27.

Balmer O, Stearns SC, Schotzau A & Brun R (2009) Intraspecific competition between co-infecting parasite strains enhances host survival in African trypanosomes. Ecology 90, 3367-3378. PM:20120806

Barker RH, Jr., Liu H, Hirth B, Celatka CA, Fitzpatrick R, Xiang Y, Willert EK, Phillips MA, Kaiser M, Bacchi CJ, Rodriguez A, Yarlett N, Klinger JD & Sybertz E (2009) Novel S-adenosylmethionine decarboxylase inhibitors for the treatment of human African trypanosomiasis. Antimicrob Agents Chemother 53, 2052-2058. PM:19289530

Berger H, Seebacher W, Kaiser M, Brun R, Saf R & Weis R (2009) SARs of the antiprotozoal action of 6,7-diaryl-bicyclo[2.2.2]octan-2-ols. Monatsh Chem 140, 495-502.

Cavalli A, Lizzi F, Bongarzone S, Brun R, Luise Krauth-Siegel R & Bolognesi ML (2009) Privileged structure-guided synthesis of quinazoline derivatives as inhibitors of trypanothione reductase. Bioorg Med Chem Lett 19, 3031-3035. PM:19414258

Chavain N, Davioud-Charvet E, Trivelli X, Mbeki L, Rottmann M, Brun R & Biot C (2009) Antimalarial activities of ferroquine conjugates with either glutathione reductase inhibitors or glutathione depletors via a hydrolyzable amide linker. Bioorg Med Chem 17, 8048-8059. PM:19864147

Christen M, Adams M, Zimmermann S, Brun R & Hamburger M (2009) HPLC based activity profiling of Ganoderma lucidum extract for antiplasmodial activity and isolation of new active lanostane triterpenoids. Planta Medica 75, 948.

Dardonville C, Fernandez-Fernandez C, Gibbons SL, Jagerovic N, Nieto L, Ryan G, Kaiser M & Brun R (2009) Antiprotozoal activity of 1-phenethyl-4-aminopiperidine derivatives. Antimicrob Agents Chemother 53, 3815-3821. PM:19564359

Eberle C, Burkhard JA, Stump B, Kaiser M, Brun R, Krauth-Siegel RL & Diederich F (2009) Synthesis, inhibition potency, binding mode, and antiprotozoal activities of fluorescent inhibitors of trypanothione reductase based on mepacrine-conjugated diaryl sulfide scaffolds. ChemMedChem 4, 2034-2044. PM:19847846

Efange SM, Brun R, Wittlin S, Connolly JD, Hoye TR, McAkam T, Makolo FL, Mbah JA, Nelson DP, Nyongbela KD & Wirmum CK (2009) Okundoperoxide, a bicyclic cyclofarnesylsesquiterpene endoperoxide from Scleria striatinux with antiplasmodial activity. J Nat Prod 72, 280-283. PM:19199815

Faist J, Seebacher W, Kaiser M, Brun R, Saf R & Weis R (2009) Bicyclic amido compounds with antiprotozoal activity. Monatshefte fur Chemie 140, 1261-1268.

Faist J, Seebacher W, Schlapper C, Kaiser M, Brun R, Saf R & Weis R (2009) Antiplasmodial and antitrypanosomal activity of bicyclic amides and esters of dialkylamino acids. Bioorg Med Chem 17, 3595-3603. PM:19395265

Gachet MS, Schuhly W, Kunert O, Kaiser M, Brun R, Munoz RA & Bauer R (2009) Jacaranone derived glucosidic esters from Jacaranda glabra. Planta Medica 75, 901-902.