Mathematical models to define new malaria immunotherapies and interventions to meet public health needs

Despite recent progress in fighting malaria, there remains a need for new antimalarial interventions to protect children and other vulnerable populations who experience the highest burden of malaria.

Developing new interventions is time-consuming and costly, and it is often unclear what the public...

Ongoing
01.02.2021 - 31.01.2024
Research project
Disease Modelling
Melissa Penny
Boavista - Survive and Thrive Boa Vista Early Childhood Program

 

Background:  A growing body of evidence suggests that early life health and developmental outcomes can be improved through parental support programs. The objective of this project was to test the feasibility, impact, and relative cost-effectiveness of home visiting programs as well as center-based...

Ongoing
01.02.2021 - 31.12.2022
Intervention Study
Grand Challenges Canada
Household Economics and Health Systems Research
Günther Fink
AMED - Outlining the institutional set up for the AMED scheme along with its functions and functionaries

Chad Government is engaged in an ambitious reform to make the Universal Health Coverage (UHC) legislation operational with its three pillars defined as follows: a) contribution-based scheme for the formal sector, b) contribution-based scheme for the self-employed (informal sector) and c)...

Ongoing
22.12.2020 - 29.04.2021
Short term service project
Health Systems Support
Damien Revault
openIMIS Implementation - Expanding the knowledge base and increasing implementations

As more countries strive for Universal Health Coverage and Universal Social Protection, the number of interested and engaged stakeholders increases, adding to the organizational complexity of healthcare systems. The openIMIS (Opensource Insurance Management Information System) Initiative presents an...

Ongoing
04.12.2020 - 31.08.2022
Long term service project
Health Systems Support
Siddharth Srivastava , Helen Prytherch
openIMIS Capacity Building - Global online training course for openIMIS

As more countries stive for UHC and USP, the number of interested and engaged stakeholders increases, adding to the organizational complexity of healthcare systems. The OpenIMIS Initiative presents an Information and Communications Technology solution for managing complex (small or large)...

Ongoing
04.12.2020 - 28.02.2022
Long term service project
Deutsche Gesellschaft für Internationale Zusammenarbeit (GIZ) GmbH
Health Systems Support
Siddharth Srivastava , Helen Prytherch
ComBaCaL - Community-Based chronic disease Care Lesotho: A 5-year implementation research programme to tackle non-communicable diseases in rural Lesotho

Non-Communicable Diseases (NCDs) such as diabetes and high blood pressure are the number one cause of death and disability globally. More than 75% of premature NCD-related deaths occur in low- and middle-income countries. A new programme mainly funded by the Swiss Agency for Development and...

Ongoing
01.12.2020 - 31.12.2025
Clinical Trial, Evaluation project, PhD project, Research project, Teaching and training project
International HIV and Chronic Disease Care
Niklaus Labhardt , Alain Amstutz
GenLes - Using Viral Genetics to Curb the HIV Epidemic in Lesotho, South Africa

Major progress in curbing the HIV epidemic in Lesotho, Southern Africa has been achieved. However, there were still 11'000 new infections in 2019, emphasizing the importance of targeted prevention of new infections.

Within this project, the first aim is to combine phylogenetical tools and biological...

Ongoing
01.12.2020 -
Research project
International HIV and Chronic Disease Care
Nadine Bachmann
Manipulation of Human Immunity by Parasitic Worms

Approximately ten percent of the world's population is at risk of schistosomiasis, a neglected, tropical disease caused by species of the helminth Schistosoma. For the past 40 years, control of schistosomiasis has depended on the widespread use of a single drug, praziquantel. Despite its good...

Ongoing
01.12.2020 - 30.09.2021
Research project
Helminth Drug Development
Anna van Beek , Jennifer Keiser
EXPAND Chad - Expanding NTD and COVID-19 control to mobile pastoralists in Chad

The EXPAND project aims to expanding neglected tropical diseases (NTDs) and COVID-19 surveillance and control to mobile pastoralists in Chad through the establishment of integrated surveillance and access to health information and services. It also works towards the prevention and treatment of...

Ongoing
01.11.2020 - 31.03.2022
Long term service project
Foreign, Commonwealth & Development Office (FCDO), former Department for International Development UK (DFID) / Ascend - Accelerating the Sustainable Control and Elimination of Neglected Tropical Diseases
Health Systems Support
Peter Steinmann
SORMAS - Implementation of SORMAS in Switzerland

A majorty of cantons in Switzerland and the Fürstentum Liechtenstein have introduced the application Surveillance, Outbreak Response Management and Analysis System (SORMAS) in the course of 2020 in the frame of control measures against the Covid-19 pandemic. SORMAS allows for a structured...

Ongoing
01.11.2020 - 30.06.2021
Short term service project
Helmholtz-Zentrum für Infektionsforschung , Kanton Luzern , Kantonsarztamt Kanton Bern
Swiss Centre for International Health
Kaspar Wyss
Anemia Prevention - Identify Bottlenecks of Anemia Prevention and Control in the West Bank and Gaza

In response to the Ministry of Health request, this World Bank mandate planned over September 2020 to March 2021 intends to identify bottlenecks related to anemia prevention and control in the West Bank and Gaza - Swiss TPH is partnering with researchers from two experienced local organizations: the...

Ongoing
19.10.2020 - 31.05.2021
Short term service project
World Bank (WB)
Systems Performance and Monitoring
Odile Pham-Tan
BAG KEA - Competence Centre for Epidemiological Outbreak Investigations

In Switzerland, foodborne infections such as listeriosis, salmonellosis or campylobacteriosis are notifiable diseases and are under close surveillance by the Swiss Federal Office of Public Health (FOPH). Annually, one to three outbreaks of one of these diseases have been observed in Switzerland....

Ongoing
10.10.2020 - 01.10.2021
Long term service project
Federal Office of Public Health (FOPH) / Bundesamt für Gesundheit (BAG)
Human Resources for Health
Helena Greter
Digital Technology - Policy and Technology Assessment of National Health Insurance Information Systems

There is a strong movement to apply digital technologies as a means of strengthening health systems and social protection delivery, in Low- and Middle-Income Countries (LMICs) including innovations for demand generation, better management of information, and improved efficiency of health workers. ...

Ongoing
05.10.2020 - 31.07.2022
Long term service project, Evaluation project
Asian Development Bank (ADB)
Health Systems Support
Siddharth Srivastava
Healthy Life Project, Phase II - Healthy Life Project, Phase II: Reducing the Burden of Non-Communicable Diseases in the Republic of Moldova

Background
Non-communicable diseases (NCDs) are the leading cause of death worldwide. Like many countries, the Republic of Moldova faces a growing NCD mortality and morbidity burden: more than half of the population suffers from non-communicable diseases, including cardiovascular diseases, cancer,...

Ongoing
01.10.2020 - 30.09.2024
Long term service project
Human Resources for Health
Helen Prytherch
ADOPT - Adoption of Levo-Praziquantel 150mg for schistosomiasis by endemic countries (ADOPT)

Schistosomiasis is a neglected tropical disease that poses a serious public health challenge. Current treatment recommendations and control efforts focus on distribution of praziquantel tablets to school-aged children and at-risk populations. Preschool-aged (≤5 years) children (PSAC) represent...

Ongoing
01.10.2020 - 30.09.2022
Long term service project
Global Health Innovative Technology Fund (GHIT)
Human Resources for Health
Peter Steinmann
MOOC IRM - Massive Open Online Course on Insecticide Resistance Management

 

The Global Plan for Insecticide Resistance Management (GPIRM) (WHO 2012) is the authoritative resource for Insecticide Resistance Management (IRM) in the mosquito vectors of malaria. However, IRM is an applied science, and there is a need to translate theory into practice. Whilst there are...

Ongoing
01.10.2020 - 31.03.2021
Teaching and training project
Innovative Vector Control Consortium (IVCC)
Health Interventions
Konstantina Boutsika
MR Gavi - Monitoring Review - Sao Tome and Principe

Following a Gavi Programme Capacity Assessment (PCA) performed in April 2016 by Swiss TPH covering Programme Management, Financial Management as well as Vaccines and Cold Chain Management (VCCM). Concrete measures were decided to improve the management of Gavi grants including more specifically the...

Ongoing
01.10.2020 - 31.12.2021
Long term service project
Global Alliance for Vaccines and Immunization (GAVI)
Systems Performance and Monitoring
Odile Pham-Tan
Multifaceted impacts of COVID-19 on bottom forty percent income residents in Malaysia: inequities and co-benefits of interventions

The aim of this project is to contribute to a better understanding of the multifaceted impacts of COVID-19 crisis among the bottom low-income urban communities in Malaysia and improve the benefits from public health interventions. The specific objectives are: (i)- To analyze the available...

Ongoing
01.09.2020 - 31.08.2021
Research project
State Secretariat for Education, Research and Innovation (SERI); Staatssekretatiat für Bildung, Forschung und Innovation (SBFI) / Zurich University of Applied Sciences (FHNW) Leading House for South Asia and Iran
Ecosystem Services, Climate and Health
Guéladio Cissé
ARQ_2021 - Kinase Inhibitors for Adjunct Antibiotic Treatment of Tuberculosis

Tuberculosis (TB) encompasses pulmonary and extra-pulmonary infections by the deadly obligate human pathogen Mycobacterium tuberculosis (MTB). Upon exposure to infectious aerosols, host immune responses build up multi-cellular structures called granulomas that aim to encapsulate the bacteria at the...

Ongoing
01.09.2020 - 31.08.2021
Research project
Novartis Foundation for medical-biological research
Tuberculosis Research Unit, Tuberculosis Immunology
Damien Portevin
Agent-based tracking of disease spread with dynamic models of travel behaviour in a pandemic

Epidemic models are essential tools to coordinate all aspects of the response to pandemics. Models can inform policy makers on strategies for vaccinations and testing, but also to trigger mitigation measure such as the ‘lockdowns’ used during the COVID-19 outbreak in Switzerland. Here, we propose to...

Ongoing
01.09.2020 - 31.08.2022
Research project
Swiss National Science Foundation (SNSF) / Programme NRP