Transcriptomic and lipidomic profiles of glycerolipids during <em>Arabidopsis</em> flower development (Publications)
Flower glycerolipids are the yet-to-be discovered frontier of the lipidome. Although ample evidence suggests important roles for glycerolipids in flower development, stage-specific lipid profiling in
A broadly-protective vaccine against meningococcal disease in sub-Saharan Africa based on generalised modules for membrane antigens (GMMA) (Publications)
INTRODUCTION: Neisseria meningitidis causes epidemics of meningitis in sub-Saharan Africa. These have mainly been caused by capsular group A strains, but W and X strains are increasingly contributing
Medicinal chemistry optimization of antiplasmodial imidazopyridazine hits from high throughput screening of a SoftFocus kinase library: part 1 (Publications)
A novel class of imidazopyridazines identified from whole cell screening of a SoftFocus kinase library was synthesized and evaluated for antiplasmodial activity against K1 (multidrug resistant strain)
2,4-diaminothienopyrimidines as orally active antimalarial agents (Publications)
A novel series of 2,4-diaminothienopyrimidines with potential as antimalarials was identified from whole-cell high-throughput screening of a SoftFocus ion channel library. Synthesis and structure-acti
<em>Paragonimus paishuihoensis</em> metacercariae in freshwater crabs, <em>Potamon lipkei</em>, in Vientiane Province, Lao PDR (Publications)
Among Paragonimus species, P. paishuihoensis is one of the most mysterious and poorly understood species. Metacercariae are characterized by having a unique dendritically branched excretory bladder. H
<em>In vitro</em> efficacy of dicationic compounds and mefloquine enantiomers against <em>Echinococcus multilocularis</em> metacestodes (Publications)
The current chemotherapy of alveolar echinococcosis (AE) is based on benzimidazoles such as albendazole and has been shown to be parasitostatic rather than parasiticidal, requiring lifelong duration.
Effect of sampling and diagnostic effort on the assessment of schistosomiasis and soil-transmitted helminthiasis and drug efficacy: a meta-analysis of... (Publications)
SUMMARY It is generally recommended to perform multiple stool examinations in order to improve the diagnostic accuracy when assessing the impact of mass drug administration programmes to control human
Occupational exposures and uncontrolled adult-onset asthma in the European Community Respiratory Health Survey II (Publications)
Occupational exposure is a well-recognised modifiable risk factor for asthma, but the relationship between occupational exposure and asthma control has not been studied. We aimed to study this associa