<em>In vivo</em> and <em>in vitro</em> sensitivity of <em>Fasciola hepatica</em> to combinations of triclabendazole and artesunate, artemether or OZ78 (Publications)
Triclabendazole resistance is continually documented from livestock and hence new treatment strategies for F. hepatica infections are needed. We investigated the effect of combinations with triclabend
Past, present, and future of Japanese encephalitis (Publications)
Japanese encephalitis (JE), a vector-borne viral disease, is endemic to large parts of Asia and the Pacific. An estimated 3 billion people are at risk, and JE has recently spread to new territories. V
Heterochromatin silencing and locus repositioning linked to regulation of virulence genes in <em>Plasmodium falciparum</em> (Publications)
The malaria parasite Plasmodium falciparum undergoes antigenic variation to evade host immune responses through switching expression of variant surface proteins encoded by the var gene family. We demo
Symptoms and transmission of intestinal cryptosporidiosis (Publications)
Cryptosporidium spp are a cause of diarrhoea in toddlers. Symptoms and routes of transmission were investigated in a prospective case-control study in the city and surroundings of Basel, Switzerland.
Field evaluation of a recombinant glutathione S-transferase-based pyrethroid quantification assay (Publications)
A recombinant glutathione S-transferase (GST)-based pyrethroid quantification assay was field-tested in Ifakara, Tanzania. Initial laboratory tests suggested that all reagents used in the assay should
Owner valuation of rabies vaccination of dogs, Chad (Publications)
We estimated the association between amount charged and probability that dog owners in N'Djamena, Chad, would have their dogs vaccinated against rabies. Owners would pay approximately 400-700 CFA fran
Synthesis, inhibition potency, binding mode, and antiprotozoal activities of fluorescent inhibitors of trypanothione reductase based on... (Publications)
Trypanothione reductase (TR) is a flavoenzyme unique to trypanosomatid parasites and a target for lead discovery programs. Various inhibitor scaffolds have emerged in the past, exhibiting moderate aff