A high-resolution geospatial surveillance-response system for malaria elimination in Solomon Islands and Vanuatu (Publications)
provinces of Isabel and Temotu, Solomon Islands and Tafea, Vanuatu. Confirmed malaria cases were reported to provincial malaria offices upon diagnosis and updated into the respective SDSS as part of routine [...] surveillance-response system has been developed within a geographic information system (GIS) to support malaria elimination in the Pacific. This paper examines the application of a GIS-based spatial decision support [...] support system (SDSS) to automatically locate and map the...
A research agenda for malaria eradication: monitoring, evaluation, and surveillance (Publications)
how well public health programs operate over time and achieve their goals. As countries approach malaria elimination, these activities will need to shift from measuring reductions in morbidity and mortality [...] there is a clear need to systematically review the information from past elimination efforts for malaria and other infectious diseases
Rapid urban malaria appraisal (RUMA) in sub-Saharan Africa (Publications)
BACKGROUND: The rapid urban malaria appraisal (RUMA) methodology aims to provide a cost-effective tool to conduct rapid assessments of the malaria situation in urban sub-Saharan Africa and to improve the [...] site, providing a good overview of the malaria situation. School and health facility-based surveys provided an overview of local endemicity and the overall malaria burden in different city areas. This helped [...] the understanding of urban malaria epidemiology. METHODS: This work was done...
Community-based surveillance of malaria vector larval habitats: a baseline study in urban Dar es Salaam, Tanzania (Publications)
minimal training and supervision in the first weeks of an operational urban malaria control program. METHODS: The Urban Malaria Control Programme of Dar es Salaam recruited and provided preliminary training [...] the population of Africa rapidly urbanizes it may be possible to protect large populations from malaria by controlling aquatic stages of mosquitoes. Here we present a baseline evaluation of the ability [...] CORPs at the start of the Dar es Salaam UMCP were insufficient to enable...
Inaugural meeting of the malaria policy advisory committee to the WHO: conclusions and recommendations (Publications)
conclusions and recommendations from that meeting, as part of the newly launched Malaria Journal thematic series "WHO Malaria Policy Advisory Committee: Reports and Recommendations".Summaries are provided [...] sessions on global malaria control, drug resistance and containment, rapid diagnostic test procurement criteria, larviciding, classification of countries for elimination, estimating malaria cases and deaths [...] The Malaria Policy Advisory Committee to the World Health Organization met...
Evidence of blood stage efficacy with a virosomal malaria vaccine in a phase IIa clinical trial (Publications)
indicates that a combination vaccine targeting different stages of the malaria life cycle is likely to provide the most effective malaria vaccine. This trial was the first to combine two existing vaccination [...] ts were healthy, malaria naive volunteers, from Oxford. The interventions were vaccination with PEV3A alone, or PEV3A+FFM ME-TRAP. The main outcome measure was protection from malaria in a sporozoite challenge [...] stages of the P. falciparum life cycle. METHODS: This was a Phase...
Malaria surveillance-response strategies in different transmission zones of the People's Republic of China: preparing for climate change (Publications)
understanding of malaria transmission patterns in the People's Republic of China (P.R. China) is crucial for designing effective surveillance-response strategies that can guide the national malaria elimination [...] survival derived from monthly mean temperature and YRH were generated. For each decade, the final malaria prediction map was overlaid by two mask maps, in terms of number of months suitable for parasite [...] 60%. RESULTS: Considering multiple environmental factors simultaneously,...
Towards malaria elimination: a new thematic series (Publications)
launch of a new thematic series of Malaria Journal -- "Towards malaria elimination" -- creates the forum that allows carrying scientific evidence on how to achieve malaria elimination in specific endemic
Measures of clinical malaria in field trials of interventions against <em>Plasmodium falciparum</em> (Publications)
IIb or III malaria vaccine trials were simulated corresponding to each of a pre-erythrocytic, blood stage, and anti-disease vaccine, each in a population with 80% prevalence of patent malaria infection [...] BACKGROUND: Standard methods for defining clinical malaria in intervention trials in endemic areas do not guarantee that efficacy estimates will be unbiased, and do not indicate whether the intervention [...] between morbidity and parasite density and the performance of different case...
Agrochemicals against malaria, sleeping sickness, leishmaniasis and Chagas disease (Publications)
In tropical regions, protozoan parasites can cause severe diseases with malaria, leishmaniasis, sleeping sickness, and Chagas disease standing in the forefront. Many of the drugs currently being used to