Comparison of axillary, rectal and tympanic temperature measurements in children admitted with malaria (Publications)
We compared axillary, rectal and tympanic temperatures in children admitted with severe malaria. The axillary temperatures were 0.74 degrees C (95% limits of agreement -0.85 to 2.33 degrees C) less than
The effects of untreated bednets on malaria infection and morbidity on the Kenyan coast (Publications)
protected against both malaria infection and clinical disease compared with children not sleeping under bednets. The study was conducted in Kilifi District, Kenya, during the malaria season (June-August, [...] P = 0.47). When these same children were followed-up during the malaria season, there was evidence of a lower rate of clinical malaria among those that used untreated nets in good condition (adjusted [...] or = 10 years. Data collected from a cross-sectional survey showed evidence of...
Peripheral blood dendritic cells in children with acute <em>Plasmodium falciparum</em> malaria (Publications)
children suffering from acute malaria in Kilifi, Kenya. Comparable percentages of CD83(+) DCs were found in peripheral blood of healthy children and children with malaria. However, the percentage of HLA-DR(+) [...] qualitative and quantitative analysis of these cells in various human diseases. Plasmodium falciparum malaria is characterized by the poor induction of long-lasting protective immune responses. This study, therefore [...] HLA-DR(+) peripheral blood DCs was significantly reduced in...
<em>Plasmodium falciparum</em>: malaria morbidity is associated with specific merozoite surface antigen 2 genotypes (Publications)
vaccine against blood stage malaria. In order to test if a specific genotype of the highly polymorphic MSA2 is associated with disease, we conducted a case-control study in a malaria endemic area of Papua New [...] as likely to be found in symptomatic malaria cases than in asymptomatic controls. Mixed genotype infections were significantly less frequent in symptomatic malaria infections. One individual allele (WOS10) [...] to lack of immunity to it. This study provides evidence that MSA2 is...
<em>Plasmodium falciparum</em>: extensive polymorphism in merozoite surface antigen 2 alleles in an area with endemic malaria in Papua New Guinea (Publications)
falciparum: Extensive polymorphism in merozoite surface antigen 2 alleles in an area with endemic malaria in Papua New Guinea. Experimental Parasitology 79, 106-116. The prevalence of Plasmodium falciparum