Global action for training in malaria elimination [Commentary] (Publications)
The Rethinking Malaria Leadership Forum, held at Harvard Business School in February 2017 with collaboration of the Barcelona Institute for Global Health and the Swiss Tropical and Public Health Institute [...] training gap as a high priority for both analysis and action. The gap in human resource training for malaria elimination needs to be addressed in order to assure continued progress. This paper identifies major [...] assist in filling the training gaps, and proposes global actions to...
Human migration and the spread of malaria parasites to the New World (Publications)
We examined the mitogenomes of a large global collection of human malaria parasites to explore how and when Plasmodium falciparum and P. vivax entered the Americas. We found evidence of a significant [...] contribution of African and South Asian lineages to present-day New World malaria parasites with additional P. vivax lineages appearing to originate from Melanesia that were putatively carried by the
Converging human and malaria vector diagnostics with data management towards an integrated holistic One Health approach (Publications)
Monitoring malaria prevalence in humans, as well as vector populations, for the presence of Plasmodium, is an integral component of effective malaria control, and eventually, elimination. In the field [...] precisely, the causative agent of fever, thereby differentiating among several candidate (also non-malaria) febrile diseases. This requires genetic-based pathogen identification and multiplexed analysis,
Longitudinal estimation of <em>Plasmodium falciparum </em>prevalence in relation to malaria prevention measures in six sub-Saharan African countries (Publications)
(PfPR) is a widely used metric for assessing malaria transmission intensity. This study was carried out concurrently with the RTS,S/AS01 candidate malaria vaccine Phase III trial and estimated PfPR over [...] 3 sites. Surveys were usually performed during the peak malaria parasite transmission season, in one home visit, when medical history and malaria risk factors/prevention measures were collected, and a blood [...] 0.52, 0.68, 0.41) and bed net use in 2 surveys (ORs: 0.63, 0.68, 1.03, 1.78)...
Improving malaria home treatment by training drug retailers in rural Kenya (Publications)
Recent global malaria control initiatives highlight the potential role of drug retailers to improve access to early effective malaria treatment. We report on the findings and discuss the implications of [...] of private drug retailers in control strategies aiming to improve prompt effective treatment of malaria
Efficacy and safety of artemether-lumefantrine in the treatment of acute, uncomplicated <em>Plasmodium falciparum </em>malaria: a pooled analysis (Publications)
and safety of artemether-lumefantrine (AL) for treatment of uncomplicated Plasmodium falciparum malaria. Data from seven studies supported by Novartis (1996-2007), including 647 adults (> 16 years of age
Towards empirical description of malaria seasonality in southern Africa: the example of Zimbabwe (Publications)
BACKGROUND: Quantitative description and mapping of malaria seasonality is important for timely spatial targeting of interventions and for modelling malaria risk. There is a need for seasonality models that [...] use Zimbabwe as an example for developing an empirical map of malaria seasonality. We describe the relationship between seasonality in malaria and environmental covariates for the period 1988--1999, by fitting [...] seasonal trend. We adapt a seasonality concentration index used...
Socially marketed insecticide-treated nets improve malaria and anaemia in pregnancy in southern Tanzania (Publications)
CONCLUSIONS: A modest impact of ITNs on pregnancy malaria and anaemia was shown in our high malaria transmission setting. The development of ITN programmes for malaria control should include pregnant women as a [...] no anaemia, and of high density, low density and no malaria infection by ITN status. Recently treated nets were most effective at preventing malaria and anaemia (prevalence of mild anaemia was 68% compared [...] OBJECTIVES: To study the uptake of socially marketed...