<em>Plasmodium falciparum</em> genetic diversity in western Kenya highlands (Publications)
microsatellite loci and two antigen loci. Malaria in highland areas is unstable and epidemic whereas malaria in lowland areas is endemic. Transmission intensity and malaria prevalence are substantially lower
<em>Plasmodium falciparum</em> genetic diversity in western Kenya highlands (Publications)
microsatellite loci and two antigen loci. Malaria in highland areas is unstable and epidemic whereas malaria in lowland areas is endemic. Transmission intensity and malaria prevalence are substantially lower
The spiroindolone drug candidate NITD609 potently inhibits gametocytogenesis and blocks <em>Plasmodium falciparum</em> transmission to Anopheles... (Publications)
The global malaria agenda has undergone a reorientation from control of clinical cases to entirely eradicating malaria. For that purpose, a key objective is blocking transmission of malaria parasites from
Comparison of diagnostic methods for the detection and quantification of the four sympatric <em>Plasmodium</em> species in field samples from Papua... (Publications)
Plasmodium infections is essential for malaria morbidity and mortality reduction in tropical areas. Despite great advantages of light microscopy (LM) for malaria diagnosis, its limited sensitivity is a [...] P. malariae and P. ovale. P. falciparum and P. vivax prevalence by qPCR was 40.9% and 65.7% respectively. This compares to 43.8% and 73.2% by nPCR and 47.1% and 67.5% by PCR_LDR_FMA. P. malariae and P [...] LM was lower for all four species, being 25.4% for P. falciparum, 54.9% for P....
Bayesian Modelling and Analysis (Page)
https://www.swisstph.ch/de/about/eph/biostatistics/bayesian-modelling-and-analysis
factors on malaria mortality at different spatial scales in western Kenya, 2008-2019. BMJ Glob Health . 2024;9(9):e014614. DOI: 10.1136/bmjgh-2023-014614 Nyawanda B.O et al. The influence of malaria control [...] Group | Bayesian Modelling and Analysis Predicted Risk Map of Malaria Parasite among Children under 5 year in Nigeria Biostatistics Bayesian Modeling and Analysis Statistics in Epidemiology The Bayesian [...] research area of the group. It involves developing data-driven statistical...
Comparison of diagnostic methods for the detection and quantification of the four sympatric <em>Plasmodium</em> species in field samples from Papua... (Publications)
Plasmodium infections is essential for malaria morbidity and mortality reduction in tropical areas. Despite great advantages of light microscopy (LM) for malaria diagnosis, its limited sensitivity is a [...] P. malariae and P. ovale. P. falciparum and P. vivax prevalence by qPCR was 40.9% and 65.7% respectively. This compares to 43.8% and 73.2% by nPCR and 47.1% and 67.5% by PCR_LDR_FMA. P. malariae and P [...] LM was lower for all four species, being 25.4% for P. falciparum, 54.9% for P....
Effect of artemether administered alone or in combination with praziquantel to mice infected with <em>Plasmodium berghei </em>or <em>Schistosoma... (Publications)
treatment and control of malaria, particularly within artemisinin-based combination therapies. Since the artemisinins also exhibit antischistosomal properties, their use in areas where malaria and schistosomiasis [...] in areas where malaria and schistosomiasis co-exist and where artemisinin-based combination therapies are introduced, since artemisinin-based combination therapies as part of a malaria control package
Analysis of <em>Plasmodium falciparum</em> var genes expressed in children from Papua New Guinea (Publications)
sequences was detected in symptomatic malaria, and a subgroup of frequently encountered var genes with complex head structure seems to be associated with severe malaria. A subset of var group C genes was [...] variable antigen P. falciparum erythrocyte membrane protein-1 (PfEMP1) is a major virulence factor in malaria. A large number of var genes encode PfEMP1, and we hypothesized that a restricted PfEMP1 repertoire [...] children. METHODS: var messenger RNA was isolated from 78 children with...
Analysis of <em>Plasmodium falciparum</em> var genes expressed in children from Papua New Guinea (Publications)
sequences was detected in symptomatic malaria, and a subgroup of frequently encountered var genes with complex head structure seems to be associated with severe malaria. A subset of var group C genes was [...] variable antigen P. falciparum erythrocyte membrane protein-1 (PfEMP1) is a major virulence factor in malaria. A large number of var genes encode PfEMP1, and we hypothesized that a restricted PfEMP1 repertoire [...] children. METHODS: var messenger RNA was isolated from 78 children with...
Effect of artemether administered alone or in combination with praziquantel to mice infected with <em>Plasmodium berghei </em>or <em>Schistosoma... (Publications)
treatment and control of malaria, particularly within artemisinin-based combination therapies. Since the artemisinins also exhibit antischistosomal properties, their use in areas where malaria and schistosomiasis [...] in areas where malaria and schistosomiasis co-exist and where artemisinin-based combination therapies are introduced, since artemisinin-based combination therapies as part of a malaria control package