Activity refinement of aryl amino acetamides that target the <em>P. falciparum</em> STAR-related lipid transfer 1 protein (Publications)
Malaria is a devastating disease that causes significant morbidity worldwide. The development of new antimalarial chemotypes is urgently needed because of the emergence of resistance to frontline therapies [...] a useful tool for further investigating the druggability of PfSTART1 across the lifecycle of the malaria parasite.
Longitudinal tracking and quantification of individual <em>Plasmodium falciparum </em>clones in complex infections (Publications)
falciparum strains in multi-clonal infections is essential for investigating infection dynamics of malaria. The traditional genotyping techniques did not permit tracking changes in individual clone density [...] longitudinally by Amp-Seq despite MOI > 1, thus providing an additional parameter for investigating malaria infection dynamics. Amp-Seq based genotyping of longitudinal samples improves detection of minority
Mansonella perstans-Filariose nach Aufenthalt in Kamerun. 19-jährige Patientin, geboren in Kamerun, seit zehn Jahren in der Schweiz (Publications)
g pain in the lower abdomen, predominantly on the right side. A blood smear tested for presumed malaria showed subperiodic microfilariae of the species Mansonella perstans. The patient was treated with
Mansonella perstans-Filariose nach Aufenthalt in Kamerun. 19-jährige Patientin, geboren in Kamerun, seit zehn Jahren in der Schweiz (Publications)
g pain in the lower abdomen, predominantly on the right side. A blood smear tested for presumed malaria showed subperiodic microfilariae of the species Mansonella perstans. The patient was treated with
Statistics in Epidemiology Group | Biostatistics at Swiss TPH (Page)
https://www.swisstph.ch/de/about/eph/biostatistics/statistics-in-epidemiology
analysis of cohorts, and in applications in non-communicable disease and infectious diseases such as malaria. The group runs statistics courses in the Faculty of Science and contributes to postgraduate courses [...] Maximise Universal Access Long-lasting insecticidal nets (LLINs), or bed nets, are the mainstay of malaria control. However, more than 50% of people living in endemic areas are currently unprotected because [...] lifespan. The goal of the ViALLIN MUsAcc project is to develop a...
Synthesis of antimalarial 1,2,4-trioxanes via photooxygenation of a chiral allylic alcohol (Publications)
series of monocyclic and spirobicyclic 1,2,4-trioxanes (5, 6). Two products show significant anti-Malaria activity against Plasmodium falciparum when compared with chloroquine
Synthesis of antimalarial 1,2,4-trioxanes via photooxygenation of a chiral allylic alcohol (Publications)
series of monocyclic and spirobicyclic 1,2,4-trioxanes (5, 6). Two products show significant anti-Malaria activity against Plasmodium falciparum when compared with chloroquine
Bicyclic amido compounds with antiprotozoal activity (Publications)
tested for their activities against the causative organisms of East African trypanosomiasis and malaria tropica. The acylation induced in general loss of antiprotozoal activity, but a single compound showed
Bicyclic amido compounds with antiprotozoal activity (Publications)
tested for their activities against the causative organisms of East African trypanosomiasis and malaria tropica. The acylation induced in general loss of antiprotozoal activity, but a single compound showed
SARs of the antiprotozoal action of 6,7-diaryl-bicyclo[2.2.2]octan-2-ols (Publications)
tested for their activity against the causative organisms of East African sleeping sickness and malaria tropica. Structure activity relationships are discussed