Parasitic infections, anemia and malnutrition among rural settled and mobile pastoralist mothers and their children in Chad (Publications)
Chad. Intestinal parasites were evaluated using direct fecal smears and the Kato-Katz technique. Malaria status was determined using Paracheck-Pf((R)) rapid diagnostic test, and anemia was assessed with [...] common protozoan. The hookworm prevalence was 14% (CI 8-20) in women and 18% (CI 13-23) in children. Malaria prevalence was low among women (1%, CI 0.5-2) and children (3% CI 2-5). No significant difference
Parasitic infections, anemia and malnutrition among rural settled and mobile pastoralist mothers and their children in Chad (Publications)
Chad. Intestinal parasites were evaluated using direct fecal smears and the Kato-Katz technique. Malaria status was determined using Paracheck-Pf((R)) rapid diagnostic test, and anemia was assessed with [...] common protozoan. The hookworm prevalence was 14% (CI 8-20) in women and 18% (CI 13-23) in children. Malaria prevalence was low among women (1%, CI 0.5-2) and children (3% CI 2-5). No significant difference
<em>Anopheles arabiensis</em> and <em>A. gambiae</em> chromosomal inversion polymorphism, feeding and resting behaviour in relation to insecticide... (Publications)
evaluated in relation to chromosomal inversion polymorphism, feeding and resting behaviour of these malaria vectors in Tanzania. Blood-fed mosquitoes from pit traps outdoors, exit traps on windows and ind [...] of DDT was perceived as a disadvantage, whereas lambda-cyhalothrin apparently had more impact on malaria transmission by An.arabiensis.
Urban agricultural land use and characterization of mosquito larval habitats in a medium-sized town of Côte d'Ivoire (Publications)
urban dwellers. Some crop systems create suitable mosquito breeding sites and thus might affect malaria transmission. The purpose of this study was to identify, map, and characterize potential mosquito [...] and rice paddies. Our findings have important bearings for the epidemiology and control of urban malaria in sub-Saharan Africa
drLumi: an open-source package to manage data, calibrate, and conduct quality control of multiplex bead-based immunoassays data analysis (Publications)
bead-based immunoassay in a study aiming to measure correlates of risk or protection from malaria of the RTS,S malaria vaccine nested in the Phase 3 randomized controlled trial of this vaccine.
Molecular epidemiology of <em>Plasmodium falciparum</em> infections among asymptomatic inhabitans of a holoendemic malarious area in northern Ghana (Publications)
Age dependence of malaria infection was assessed in an age-stratified cluster sample of 308 individuals from Kassena-Nankana District of northern Ghana during June and July 2000. Overall prevalence of [...] holoendemic sites in Africa, validating the use of the age-multiplicity relationship as an indicator of malaria endemicity.
Antigenicity and immunogenicity of a novel <em>Plasmodium vivax</em> circumsporozoite derived synthetic vaccine construct (Publications)
BACKGROUND: The circumsporozoite (CS) protein is a major malaria sporozoite surface antigen currently being considered as vaccine candidate. Plasmodium vivax CS (PvCS) protein comprises a dimorphic central [...] VK210 and VK247. We studied the natural immune response to this region in human sera from different malaria-endemic areas and its immunogenicity in mice. RESULTS: PvNR1R2 was more frequently recognized by
Anémie dans une école du Cambodge rural: détection, prévalence et liens avec les parasitoses intestinales et la malnutrition (Publications)
iron deficiency intestinal worms and malaria. A two month transversal study was conducted in a rural primary school in Battambang Province, Cambodia, in a malaria-free area. The main objective of the study
Anti-protozoal activity of aporphine and protoberberine alkaloids from <em>Annickia kummeriae</em> (Engl. & Diels) Setten & Maas (Annonaceae) (Publications)
BACKGROUND: Malaria, trypanosomiasis and leishmaniasis have an overwhelming impact in the poorest countries in the world due to their prevalence, virulence and drug resistance ability. Currently, there [...] there is inadequate armory of drugs for the treatment of malaria, trypanosomiasis and leishmaniasis. This underscores the continuing need for the discovery and development of new anti-protozoal drugs. Consequently
Repositioning and characterization of 1-(pyridin-4-yl)pyrrolidin-2-one derivatives as <em>Plasmodium </em>cytoplasmic prolyl-trna synthetase... (Publications)
parasites at a selection pressure of 3 x IC50) constitute unfavorable features for treatment of malaria. However, potent blood stage and antischizontal activity are compelling for causal prophylaxis which [...] Encouraging preliminary off-target profile and oral efficacy in a humanized murine model of Pf malaria allowed us to conclude that 1-(pyridin-4-yl)pyrrolidin-2-one derivatives represent a promising starting
