Strategies for detection of <em>Plasmodium species</em> gametocytes (Publications)
transmission stages of malaria parasites, are determined for predicting the infectiousness of humans to mosquitoes. This measure is used for evaluating interventions that aim at reducing malaria transmission.
Interactions and potential implications of <em>Plasmodium falciparum</em>-hookworm coinfection in different age groups in south-central Côte... (Publications)
these parasitic infections is of public health relevance considering that control measures targeting malaria and helminthiases are going to scale.METHODOLOGY: A cross-sectional survey was carried out in April [...] information could have important implications when implementing integrated control measures against malaria and helminthiases.
<em>Plasmodium vivax</em> and <em>Plasmodium falciparum</em> infection dynamics: re-infections, recrudescences and relapses (Publications)
BACKGROUND: In malaria endemic populations, complex patterns of Plasmodium vivax and Plasmodium falciparum blood-stage infection dynamics may be observed. Genotyping samples from longitudinal cohort studies [...] CONCLUSION: The statistical model developed here provides a useful new tool for in-depth analysis of malaria data from longitudinal cohort studies, and future application to data sets with multi-locus genotyping
Activation of TCR Vδ1+ and Vδ1-Vδ2- γδ T cells upon controlled infection with <em>Plasmodium falciparum</em> in Tanzanian volunteers (Publications)
immune response to malaria remains incomplete. Clinical trials using whole-sporozoite-based vaccination approaches such as the Sanaria PfSPZ Vaccine, followed by controlled human malaria infection (CHMI)
qRT-PCR versus IFA-based quantification of male and female gametocytes in low-density <em>Plasmodium falciparum</em> infections and their relevance... (Publications)
Accurate quantification of female and male gametocytes and sex ratios in asymptomatic low-density malaria infections are important for assessing their transmission potential. Gametocytes often escape detection [...] negligible for human-to-mosquito transmission.Estimating the transmission potential of ultralow-density malaria infections informs interventions. Almost all infections with > /=1 female and male gametocyte per
Temporal distribution of <em>Plasmodium falciparum </em>recrudescence following artemisinin-based combination therapy: an individual participant data... (Publications)
various follow-up time-points in treatment efficacy trials for uncomplicated Plasmodium falciparum malaria. METHODS: Individual patient data from 83 anti-malarial efficacy studies collated in the WorldWide [...] constructed distribution was used to estimate the optimal follow-up period for capturing a P. falciparum malaria recrudescence. Simulation studies were conducted based on the constructed distributions to quantify
DDT contamination in water resources of some African countries and its impact on water quality and human health (Publications)
use in indoor residual spraying (IRS) in developing countries, including African countries, for malaria control. There have been no previous reviews on DDT residues in water resources in Africa. The study [...] risk in sampled drinking sources within African water systems. Therefore, alternative methods for malaria vector control should be investigated and applied.
Synthesis of novel diazabicycles and their antiprotozoal activities (Publications)
potencies against Plasmodium falciparum K-1 and Trypanosoma b. rhodesiense, the causative organisms of malaria tropica and the East African form of sleeping sickness
Antiprotozoal activities of epimeric aminobicycles (Publications)
sleeping sickness, and Plasmodium falciparum K-1, a multiresistant protozoan parasite which causes Malaria tropica. The results are compared to the activities of their formerly synthesized stereoisomers and
Safety of artemether-lumefantrine exposure in first trimester of pregnancy: an observational cohort (Publications)
s in early pregnancy. They are, therefore, not recommended by WHO as a first-line treatment for malaria in first trimester due to associated embryo-foetal toxicity in animal studies. The study assessed
