Antiprotozoal activity profiling of approved drugs: a starting point toward drug repositioning (Publications)
available to treat diseases such as leishmaniasis, Chagas' disease, human African trypanosomiasis and malaria. Since drug development is lengthy and expensive, a drug repurposing strategy offers an attractive
Prévention des infections chez les voyageurs immunosupprimés (Publications)
While traveling, patients may be exposed to several infections, such as traveler's diarrhea or malaria, which can be associated with a high rate of complications in this population. An appropriate strategy
<em>Plasmodium</em> gene regulation: far more to factor in (Publications)
Gene expression in the malaria parasite has received generous attention over the past several decades, predominantly because of the importance of var gene regulation, which is key to antigenic variation
Analogues of thiolactomycin as potential anti-malarial and anti-trypanosomal agents (Publications)
thiolactomycin (TLM) have been synthesised and evaluated for their ability to inhibit the growth of the malaria parasite, Plasmodium falciparum. Thiolactomycin is an inhibitor of Type II fatty acid synthase which
Discovery and structure-activity relationships of pyrrolone antimalarials (Publications)
2000-fold) compared to a mammalian cell line (L6), and significant activity against a rodent model of malaria when administered intraperitoneally. Structure-activity relationship studies have indicated ways
Antiprotozoal activity profiling of approved drugs: a starting point toward drug repositioning (Publications)
available to treat diseases such as leishmaniasis, Chagas' disease, human African trypanosomiasis and malaria. Since drug development is lengthy and expensive, a drug repurposing strategy offers an attractive
Prévention des infections chez les voyageurs immunosupprimés (Publications)
While traveling, patients may be exposed to several infections, such as traveler's diarrhea or malaria, which can be associated with a high rate of complications in this population. An appropriate strategy
Ensuring transmission through dynamic host environments: host-pathogen interactions in <em>Plasmodium </em>sexual development (Publications)
A renewed global commitment to malaria elimination lends urgency to understanding the biology of Plasmodium transmission stages. Recent progress toward uncovering the mechanisms underlying Plasmodium
Modifications and hybrids of 1,2,3,4‑tetrahydropyridinium salts and their antiprotozoal potencies (Publications)
were investigated for their activity against Plasmodium falciparum NF54, a causative organism of Malaria tropica and Trypanosoma brucei rhodesiense, the causative organism of Human African Trypanosomiasis
Bioactives (Page)
https://www.swisstph.ch/de/services/bioactives
collaboration with Swiss TPH include novel treatments for Buruli ulcer, human African trypanosomiasis, malaria and soil-transmitted helminths. Available Drug Efficacy Tests According to Pathogen Species Bacteria [...] mansoni T. b. rhodesiense between red blood cells Aedes aegypti Related Topics Infectious Diseases Malaria Helminths Human African Trypanosomiasis (HAT) Tuberculosis Related Activities Arthropod Testing Facility
