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Control of Helminth Infections WHO Collaborating Centre for Modelling, Monitoring and Training for Malaria Control and Elimination WHO Collaborating Centre for Verbal Autopsy Swiss TPH - Auf einen Blick
Alterations in T cell subsets in human immunodeficiency virus-infected adults with co-infections in southern Mozambique (Publications)
viruses I and II [HTLV-I/II], Kaposi sarcoma-associated herpesvirus [KSHV], Plasmodium falciparum malaria, and tuberculosis), and levels of activated CD8 and CD4 T cell subsets as well as naive and memory
Identification of a cis-acting DNA-protein interaction implicated in singular var gene choice in <em>Plasmodium falciparum</em> (Publications)
Plasmodium falciparum is responsible for the most severe form of malaria in humans. Antigenic variation of P. falciparum erythrocyte membrane protein 1 leads to immune evasion and occurs through switches
Selection and reversal of <em>Plasmodium berghei</em> resistance in the mouse model following repeated high doses of artemether (Publications)
Artemether, a derivative of artemisinin, is effectively used for the treatment of malaria without any clinically relevant resistance to date. Artemether has also been developed as an antischistosomal agent
Cyclic nucleotide-specific phosphodiesterases of <em>Plasmodium falciparum</em>: PfPDEalpha, a non-essential cGMP-specific PDE that is an integral... (Publications)
potential targets for PDE inhibitor-based anti-parasitic drugs. Genomes of the various agents of human malaria, most notably Plasmodium falciparum, all contain four genes for class 1 PDEs. The catalytic domains
Assessing seasonal variations and age patterns in mortality during the first year of life in Tanzania (Publications)
trends. Mortality rates in Sub-Sahara Africa show seasonal patterns due to high infant and child malaria-related mortality which is influenced by seasonal features present in environmental and climatic
Target product profile for a diagnostic assay to differentiate between bacterial and non-bacterial infections and reduce antimicrobial overuse in... (Publications)
group, and consensus characteristics were defined. The working group defined non-severely ill, non-malaria infected children as the target population for the desired assay. To provide access to the most patients
Insecticide susceptibility of <em>Anopheles </em>mosquitoes changes in response to variations in the larval environment (Publications)
Insecticide resistance threatens the success achieved through vector control in reducing the burden of malaria. An understanding of insecticide resistance mechanisms would help to develop novel tools and strategies
<em>Schistosoma</em>, other helminth infections, and associated risk factors in preschool-aged children in urban Tanzania (Publications)
and performed medical examinations. We performed full blood cell counts and screened for HIV and malaria. Point-of-care circulating cathodic antigen (POC-CCA), urine filtration, Kato-Katz, FLOTAC, and Baermann
Screening medicinal plants for the detection of novel antimalarial products applying the inhibition of beta-hematin formation (Publications)
identification of novel scaffolds for the development of effective and safe treatments to fight malaria is urgently needed. One of the main opportunities is the discovery of new molecules from natural
