Patient variability in the blood-stage dynamics of <em>Plasmodium falciparum </em>captured by clustering historical data (Publications)
(within-host models), and can predict the impact of control strategies that affect the blood-stage of malaria. However, the dynamics of P. falciparum blood-stage infections are highly variable between individuals
Pre-existing partner-drug resistance to artemisinin combination therapies facilitates the emergence and spread of artemisinin resistance: a consensus... (Publications)
artemisinin resistance. Each model simulates 100 000 individuals in a particular transmission setting (malaria prevalence of 1%, 5%, 10%, or 20%) with a daily time step that updates individuals' infection status
The shape of the iceberg: quantification of submicroscopic <em>Plasmodium falciparum</em> and<em> Plasmodium vivax </em>parasitaemia and... (Publications)
of low-density asymptomatic infections with concurrent gametocytes may be a stumbling block for malaria elimination. This study investigated the asymptomatic reservoir of Plasmodium falciparum and Plasmodium
Causes of hospital admission among people living with HIV worldwide: a systematic review and meta-analysis (Publications)
admission, followed by malnutrition and wasting, haematological disorders, and, in the African region, malaria. Mortality in individuals admitted to hospital was 20% (95% CI 18-23, 12?902 deaths) for adults and
2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage <em>Plasmodium</em> infections (Publications)
acid biosynthesis pathway (PfFAS-II) has recently been shown to be indispensable for liver stage malaria parasites, the inhibitory potential of the HDAs against multiple P. falciparum FAS-II (PfFAS-II)
System effectiveness of a targeted free mass distribution of long lasting insecticidal nets in Zanzibar, Tanzania (Publications)
Insecticide-treated nets (ITN) and long-lasting insecticidal treated nets (LLIN) are important means of malaria prevention. Although there is consensus regarding their importance, there is uncertainty as to which
Durability of Olyset campaign nets distributed between 2009 and 2011 in eight districts of Tanzania (Publications)
BACKGROUND: Long-lasting insecticidal nets (LLINs) are the first line choice for malaria vector control in sub-Saharan Africa, with most countries adopting universal coverage campaigns. However, there
Winter Symposium 2019 (Page)
https://www.swisstph.ch/de/about/events/winter-symposium-2019
Sokhna Thiam, Swiss TPH, Senegal 11:40 Malaria and Climate Change in West Africa, Richard M’bra Kouassi, Swiss TPH, Cote d’Ivoire Short Film “WHO: TDR - Preventing Malaria and Schistosomiasis due to Climate
Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease... (Publications)
disease, cerebrovascular disease, lower respiratory infections, diarrhoeal diseases, road injuries, malaria, neonatal preterm birth complications, HIV/AIDS, chronic obstructive pulmonary disease, and neonatal [...] alone, highlighted distinct regional patterns including the greater than expected level of YLLs from malaria and from HIV/AIDS across sub-Saharan Africa; diabetes mellitus, especially in Oceania; interpersonal
Screening open access compound libraries and repurposing drugs to identify and characterize new molecules active against schistosomiasis and other... (Publications)
Far from the baneful impact of the so-called “big three” (HIV/AIDS, tuberculosis and malaria), schistosomiasis and other worm infections, such as the soil-transmitted helminths (STH) for example, have [...] each, both compiled and provided by the non-profit product development partnership Medicines for Malaria Venture (MMV). One library, the Pathogen Box, was composed of drug-like molecules with already-known
