A multiplex assay for the sensitive detection and quantification of male and female <em>Plasmodium falciparum</em> gametocytes (Publications)
BACKGROUND: The transmission of malaria to mosquitoes depends on the presence of gametocytes that circulate in the peripheral blood of infected human hosts. Sensitive estimates of the densities of female
2-Hexadecynoic acid inhibits plasmodial FAS-II enzymes and arrests erythrocytic and liver stage <em>Plasmodium</em> infections (Publications)
acid biosynthesis pathway (PfFAS-II) has recently been shown to be indispensable for liver stage malaria parasites, the inhibitory potential of the HDAs against multiple P. falciparum FAS-II (PfFAS-II)
System effectiveness of a targeted free mass distribution of long lasting insecticidal nets in Zanzibar, Tanzania (Publications)
Insecticide-treated nets (ITN) and long-lasting insecticidal treated nets (LLIN) are important means of malaria prevention. Although there is consensus regarding their importance, there is uncertainty as to which
Systematic review of the entomological impact of insecticide-treated nets evaluated using experimental hut trials in Africa (Publications)
Africa, diminishing the efficacy of insecticide-treated nets (ITNs) – the primary tool for preventing malaria. The entomological efficacy of indoor vector control interventions can be measured in experimental
Mining Sudanese medicinal plants for antiprotozoal agents (Publications)
by either Chagas disease, African trypansomiasis or leishmaniasis, and more than 200 million by malaria. Most of the currently available drugs have drawbacks in terms of toxicity, limited oral availability
Household factors associated with access to insecticide-treated nets and house modification in Bagamoyo and Ulanga districts, Tanzania (Publications)
campaign. These findings are both lower than the least 80% coverage target of the Tanzania National Malaria Strategic Plan (Tanzania NMSP). In Ulanga, population access to ITNs was 92% (n = 1143) and ITNs
Semi-field evaluation of freestanding transfluthrin passive emanators and the BG sentinel trap as a "push-pull control strategy" against <em>Aedes... (Publications)
push-pull system. Push-pull systems have been shown to reduce house entry and outdoor biting rates of malaria vectors and so have the potential to control other outdoor biting mosquitoes such as Aedes aegypti
CDC light traps underestimate the protective efficacy of an indoor spatial repellent against bites from wild <em>Anopheles arabiensis </em>mosquitoes... (Publications)
BACKGROUND: Methods for evaluating efficacy of core malaria interventions in experimental and operational settings are well established but gaps exist for spatial repellents (SR). The objective of this
Mode of action of synthetic antimalarial peroxides (Publications)
Malaria is one of the most widespread infectious diseases which caused an estimated 212 million cases and 429,000 deaths worldwide in 2015. Today, artemisinin-based combination therapy (ACT), a combination
Burden of soil-transmitted helminth infection in pregnant refugees and migrants on the Thailand-Myanmar border: results from a retrospective cohort (Publications)
is a retrospective review of records from pregnant refugee and migrant women who attended Shoklo Malaria Research Unit antenatal care (ANC) clinics along the Thailand-Myanmar border between July 2013 and