Influence of testing modality on bioefficacy for the evaluation of Interceptor® G2 mosquito nets to combat malaria mosquitoes in Tanzania (Publications)
against pyrethroid-resistant strains, demonstrating the usefulness of chlorfenapyr in mitigation of malaria.
The impact of <em>Loa loa</em> microfilaraemia on research subject retention during a whole sporozoite malaria vaccine trial in Equatorial Guinea (Publications)
300 (2.7%) residents of Bioko Island, Equatorial Guinea, during a Plasmodium falciparum sporozoite malaria vaccine clinical trial. Only one subject was found to have microfilaraemia on his first exam; parasites
Prevalence and force of <em>Plasmodium vivax</em> blood-stage infection and associated clinical malaria burden in the Brazilian Amazon (Publications)
Understanding the epidemiology of malaria through the molecular force of the blood-stage infection of Plasmodium vivax (molFOB) may provide a detailed assessment of malaria transmission. OBJECTIVES: In this [...] ed risk factors and spatial-temporal patterns of incidence of Plasmodium infection and clinical malaria episodes in three peri-urban communities of Manaus, Western Brazilian Amazon. METHODS: Monthly samples [...] Subjects who reported possession of a bed net [incidence rate ratio (IRR)...
Knowledge, attitudes and practices towards malaria diagnostics among healthcare providers and healthcare-seekers in Kondoa district, Tanzania: a... (Publications)
large-scale rollout of malaria rapid diagnostic tests (RDTs) in Tanzania, many healthcare providers (HCPs) continue using blood film microscopy (BFM) and clinical examination to diagnose malaria, which can increase [...] survey, 48% preferred using BFM for malaria testing, while 52% preferred RDT. Faced with a negative RDT result for a patient presenting with symptoms typical for malaria, 25% of HCPs stated they would confirm [...] a concern. Frequent training and supportive supervision for HCPs...
The relative impact of interventions on sympatric <em>Plasmodium vivax</em> and <em>Plasmodium falciparum</em> malaria: a systematic review (Publications)
BACKGROUND: In areas with both Plasmodium vivax and Plasmodium falciparum malaria, interventions can reduce the burden of both species but the impact may vary due to their different biology. Knowing the [...] infections attributed to P. vivax over time using a literature search. The change in the proportion of malaria attributed to P. vivax up to two years since implementation was estimated using logistic regression [...] insufficient information on interventions. There was considerable...
High-throughput <em>Plasmodium falciparum hrp2</em> and <em>hrp3 </em>gene deletion typing by digital PCR to monitor malaria rapid diagnostic test... (Publications)
Plasmodium falciparum malaria target the Histidine-Rich Proteins 2 and 3 (HRP2, HRP3). Deletions of the hrp2 and hrp3 genes result in false negative tests and are a threat for malaria control. A novel assay
Stakeholder perceptions on the deployment of multiple first-line therapies for uncomplicated malaria: a qualitative study in the health district of... (Publications)
BACKGROUND: In Burkina Faso, malaria remains the first cause of medical consultation and hospitalization in health centres. First-line case management of malaria in the country's health facilities is based [...] perspective of mitigating the emergence of artemisinin resistance, which is a serious threat to malaria control and elimination, a pilot programme using multiple first-line therapies (MFTs) [three art [...] in-depth interviews and 41 focus groups discussions, were conducted with key...
A malaria-free China: global importance and key experience (Publications)
Global Technical Strategy for Malaria 2016-2030 issued by the World Health Organization (WHO). China succeeded in its malaria elimination programme after being certified as malaria-free by the WHO on 30 June [...] Malaria has a worldwide distribution and is the world's deadliest mosquito-borne disease. The goal of malaria elimination is also reflected in the United Nations Sustainable Development Goals and the Global [...] l and socioeconomic characteristics, in order to present strong signals...