Larval and adult environmental temperatures influence the adult reproductive traits of <em>Anopheles gambiae</em> s.s. (Publications)
temperature of adults only affected the incubation period of the first egg batch. Temperature influenced the time to hatching of eggs, as well as the time to development at every stage. The number of eggs laid [...] proportion of eggs hatching after the second and third blood meal. Higher adult temperatures significantly decreased the probability of blood feeding, but the larval temperature of adults had no influence on the [...] size. Females were blood fed three times, and the number of...
The influence of zinc supplementation on morbidity due to <em>Plasmodium falciparum</em>: a randomized trial in preschool children in Papua New Guinea (Publications)
determine the influence of zinc on malaria morbidity we conducted a randomized placebo-controlled trial of daily zinc supplementation in children residing in a malaria endemic region of Papua New Guinea [...] by surveillance of cases self-reporting to a local health center. Cross-sectional surveys were conducted at the beginning, middle, and end of the study to assess infection rates, parasite density, spleen [...] > or = 100,000/microl were reduced by 69% (95% CI 25-87, P = 0.009). There was no...
Influence of MMR-vaccinations and diseases on atopic sensitization and allergic symptoms in Swiss schoolchildren (Publications)
infections in infancy or through the direct IgE-inducing effects of the vaccines. Evidence for a potential role of immunizations in the development of allergic disease is scarce. Therefore the objective was to [...] The prevalence of asthma and allergic disease has increased in many countries. It has been proposed that vaccinations may contribute to the development of allergic disease by reducing clinical infections [...] across Switzerland was organized in the framework of an environmental...
Temperature, mosquito feeding status and mosquito density influence the measured bio-efficacy of insecticide-treated nets in cone assays (Publications)
ITNs was recorded. RESULTS: There was a notable influence of temperature, feeding status and mosquito density on An. funestus mortality for both types of ITNs. Mortality at 24 h post-exposure was significantly [...] cone bioassay is routinely used to evaluate the bioefficacy of insecticide-treated nets (ITNs) for product pre-qualification and confirmation of continued ITN performance during operational monitoring. Despite [...] Despite its standardized nature, variability is often observed...
Transition bias influences the evolution of antibiotic resistance in <em>Mycobacterium tuberculosis</em> (Publications)
an overabundance of transitions relative to transversions, has been widely reported among studies of the rates and spectra of spontaneous mutations. However, demonstrating the role of transition bias in [...] antibiotic-resistance mutations. This was true at the level of mutational paths (distinct adaptive DNA sequence changes) and events (individual instances of the adaptive DNA sequence changes) and across different [...] evolution remains challenging. In particular, it is unclear whether such...
Influence of acute physical activity on stress reactivity in obese and normal weight children: a randomized controlled trial (Publications)
Physical activity (PA) may influence acute stress reactivity in children differently depending on their weight. This randomized controlled trial investigated the impact of acute PA and of BMI status (overweight/obese [...] 04). Cortisol increased in the SED, but not in the PA arm (p = 0.004 for differences in time course) of NW children. Time course did not differ between both arms in OW/OB children (p = 0.7). OW/OB SED children