Development and validation of an LC-MS/MS method for the quantification of the anthelmintic drug moxidectin in a volumetric absorptive microsample,... (Publications)
gradient program of 6 min duration. Validation was performed with respect to accuracy, precision, sensitivity, selectivity, linearity, stability, recovery, and haematocrit influence with a limit of quantification [...] sampling strategies: e.g. identical time to reach maximal concentration of 4.0 h and a similar maximal concentration of 83.9-88.5 ng/mL of moxidectin. The simple and practical capillary procedure using Mitra(R) [...] quantification of moxidectin in human blood obtained by...
Challenges of DHS and MIS to capture the entire pattern of malaria parasite risk and intervention effects in countries with different ecological... (Publications)
such as the level of mother's education, place of residence and the household welfare were captured by both surveys. CONCLUSION: Timing of the malaria survey influences estimates of the geographical d [...] malaria peak transmission season. This study compares estimates of the geographical distribution of malaria parasite risk and of the effects of interventions obtained from the DHS and MIS survey data. METHODS: [...] altitude as important predictors of the geographical distribution of the...
Informing new or improved vector control tools for reducing the malaria burden in Tanzania: a qualitative exploration of perceptions of mosquitoes and... (Publications)
BACKGROUND: The effectiveness of malaria prevention with long-lasting insecticidal nets and indoor residual spraying is limited by emerging insecticide resistance, evasive mosquito behaviours that include [...] perceived as a growing problem, directly attributed to widespread environmental deterioration and lack of effective mosquito control interventions. Malaria and nuisance biting were perceived as the main problem [...] window screens, and fumigation, while bed nets were most frequently...
High prevalence of nonconvulsive and subtle status epilepticus in an ICU of a tertiary care center: a three-year observational cohort study (Publications)
duration, length of hospital stay, outcome and case fatality rate of status epilepticus in adults in relation to demographic and clinical variables. It was conducted in an intensive care unit of a tertiary care [...] three years. RESULTS: 111 status epilepticus episodes had a median duration of 48h. Hospitalization length was 18+/-15.3 days. 81% of the status epilepticus episodes were nonconvulsive and subtle. Case fatality [...] over 70 years had independent positive influence on status...
Transposition of <em>HOPPLA</em> in siRNA-deficient plants suggests a limited effect of the environment on retrotransposon mobility in... (Publications)
powerful mutagens regarded as a major source of genetic novelty and important drivers of evolution. Yet, the uncontrolled and potentially selfish proliferation of LTR-RTs can lead to deleterious mutations [...] common in many species, the understanding of their dual role in evolution is limited. Here, we harness the genetic diversity of 320 sequenced natural accessions of the Mediterranean grass Brachypodium distachyon [...] environmental factors influence plant LTR-RT dynamics in the wild. When...
An explorative analysis of process and formulation variables affecting comilling in a vibrational mill: the case of praziquantel (Publications)
type) and process parameters (type of grinding media, grinding time and frequency) was carried out with the help of an experimental screening design. The influence of the above mentioned factors on three [...] treatment of schistosome infections, was coground in a vibrational mill with different polymers (linear and crosslinked povidone, copovidone and sodium starch glycolate). An explorative analysis of formulation [...] variation of carrier amount proved to be by far the most important...
Residential exposure to greenspace and life satisfaction in times of COVID-19: a cross-sectional analysis of 9444 participants from a population-based... (Publications)
household income, financial worries, canton of residence, or month of study entry. In addition, we assessed if the association is attributed to specific types of greenspace or accessibility to greenspace [...] important target in the COVID-19 pandemic. Residential greenness may help cope with stress and hence influence subjective well-being during this mentally and physically challenging time. METHODS: We analysed
Health-related quality of life does not explain the protective effect of farming on allergies (Publications)
in these analyses. Methods: In order to assess the potential influence of health-related quality of life (HRQOL) on the protective effect of farming, 8259 school aged children from the European GABRIEL [...] ated quality of life does not explain the protective effect of farming on allergies. Pediatr Allergy Immunol 2012: 00. ABSTRACT: Background: Numerous studies report a protective effect of farming against [...] not modify the protective effect of farming against allergies. Children with...
Development of novel multiplex microsatellite polymerase chain reactions to enable high-throughput population genetic studies of <em>Schistosoma... (Publications)
analysis of S. haematobium. The molecular resources and protocols described here advance the way researchers can perform multi locus-based population genetic analyses of S. haematobium as part of the evaluation [...] and regional elimination. The development of new high-throughput, cost-effective molecular tools and approaches are needed to monitor and evaluate the impact of control programs on the parasite populations [...] microsatellite analysis of S. haematobium larval stages stored on...
Residential exposure to greenspace and life satisfaction in times of COVID-19: a cross-sectional analysis of 9444 participants from a population-based... (Publications)
household income, financial worries, canton of residence, or month of study entry. In addition, we assessed if the association is attributed to specific types of greenspace or accessibility to greenspace [...] important target in the COVID-19 pandemic. Residential greenness may help cope with stress and hence influence subjective well-being during this mentally and physically challenging time. METHODS: We analysed