Morphometric parameters of the midgut cells of <em>Aedes aegypti </em>L. (Insecta, Diptera) under various conditions (Publications)
digestion of human serum there is no increase in the ratio of membrane-bound to free ribosomes, and no significant increase in the surface area of the rough endoplasmic reticulum or of the number of bound [...] biochemical investigations have yielded different data on the distribution of free and membrane-bound ribosomes in midgut cells of Aedes aegypti. In the present paper ribosomal distribution has been morp [...] and/or methodological errors, could account for the different results. Most of...
Spatio-temporal analysis of leprosy risks in a municipality in the state of Mato Grosso-Brazilian Amazon: results from the leprosy post-exposure... (Publications)
distribution of index cases (IC) and co-prevalent cases among contacts of leprosy patients (CP) over the course of the LPEP program in one of the four study areas in Brazil, namely the municipality of Alta Floresta [...] or 304 new cases, of which 55 were CP cases among the 2076 examined contacts. Changes over time were observed in the geographic distribution of cases. The highest concentration of cases was observed in [...] distribution was partly explained by poverty indicators. LPEP influenc...
Morphometric parameters of the midgut cells of <em>Aedes aegypti </em>L. (Insecta, Diptera) under various conditions (Publications)
digestion of human serum there is no increase in the ratio of membrane-bound to free ribosomes, and no significant increase in the surface area of the rough endoplasmic reticulum or of the number of bound [...] biochemical investigations have yielded different data on the distribution of free and membrane-bound ribosomes in midgut cells of Aedes aegypti. In the present paper ribosomal distribution has been morp [...] and/or methodological errors, could account for the different results. Most of...
A prospective study of the impact of air pollution on respiratory symptoms and infections in infants (Publications)
association of air pollution with frequency and severity of respiratory symptoms and infections measured weekly in healthy infants. Methods: In a prospective birth cohort of 366 infants of unselected mothers [...] during the first year of life (19,106 total observations). Daily mean levels of PM10, NO2 and O3 were obtained from local monitoring stations. We determined the association of the preceding week's pollutant [...] function. During times of elevated PM10 (> 33.3 microg/m(3)), duration o...
Development and validation of an enantioselective LM-MS/MS method for the analysis of the anthelmintic drug praziquantel and its main metabolite in... (Publications)
Praziquantel (PZQ) is the treatment of choice against various trematode and cestode infections. To study the pharmacokinetics of PZQ in patients infected with the liver fluke Opisthorchis viverrini, we [...] The analytes were stable in stock solutions as well as in plasma, blood and DBS. For DBS, the influences of hematocrit and blood spot size were considered as minor. Our validation results show that the [...] enantioselective liquid chromatography coupled to tandem mass spectrometry method...
Nasopharyngeal pneumococcal density is associated with viral activity but not with use of improved stoves among young Andean children (Publications)
Indoor smoke exposure is common in developing countries and may influence nasopharyngeal (NP) pneumococcal colonization density and risk of acute respiratory illness. We compared colonization density among [...] among Andean children living in households previously enrolled in a randomized controlled trial of a home intervention package including improved stoves to reduce smoke, kitchen sinks, and water disinfection
Nasopharyngeal pneumococcal density is associated with viral activity but not with use of improved stoves among young Andean children (Publications)
Indoor smoke exposure is common in developing countries and may influence nasopharyngeal (NP) pneumococcal colonization density and risk of acute respiratory illness. We compared colonization density among [...] among Andean children living in households previously enrolled in a randomized controlled trial of a home intervention package including improved stoves to reduce smoke, kitchen sinks, and water disinfection
The spatial distribution of <em>Schistosoma mansoni</em> infection in four regions of western Côte d'Ivoire (Publications)
regions of western Côte d'Ivoire; ii) to determine demographic, climatic and environmental factors that influence the distribution of S. mansoni; and iii) to map and predict the distribution of S. mansoni [...] Africa and a sound understanding of the spatial distribution facilitates to better target control interventions. The objectives of this study were i) to assess the prevalence of Schistosoma mansoni among s [...] least one Kato-Katz thick smear. The observed overall prevalence of S....
Pharmacokinetics of ascending doses of ivermectin in <em>Trichuris trichiura</em>-infected children aged 2-12 years (Publications)
treatment arms. CONCLUSIONS: A positive association of AUC or Cmax with dose was observed in both age groups. Undernutrition might influence the AUC of ivermectin in PSAC. Ivermectin shows a lower exposure [...] in changes in pharmacokinetics. However, paediatric pharmacokinetic data of ivermectin are lacking. METHODS: In the framework of a randomized controlled dose-finding trial in rural Cote d'Ivoire, Trichuris [...] BACKGROUND: Yearly, millions of children are treated globally with...
"It is difficult for us to treat their pain": health professionals' perceptions of Somali pastoralists in the context of pain management: a conceptual... (Publications)
professionals' perceptions of pain-related care for Somali pastoralists. This study seeks to understand health professionals' perceptions of Somali pastoralists in the context of pain management in Eastern [...] Pain is one of the most neglected areas of care in sub-Saharan Africa. Access to adequate pain management is important, especially in marginalised populations, such as pastoralists. Little is known about [...] model of pastoralist-specific pain management. We gave voice to pastoralists...