Glutathione transferase (GSTM1) null genotype, smoking, and prevalence of colorectal adenomas (Publications)
However, little is known of hereditary factors that influence development of common, non-Mendelian forms of this cancer. Interactions among carcinogen exposure, hereditary variants of enzymes involved in [...] time diagnosis of colorectal adenomas which are precursors to cancer. Subjects were from two Kaiser Permanente sigmoidoscopy clinics in southern California. We observed no overall effect of the GSTM1 null [...] carcinogen metabolism, and other host factors may play a role. Genetic...
Clinical aspects of 2541 patients with second stage human African trypanosomiasis (Publications)
and signs of patients with second stage HAT are described for a large cohort of patients treated in a prospective multicentre, multinational study. Special emphasis is given to the influence of disease stage [...] (duration, number of WBC in CSF) and patient age to the clinical picture. Even though the frequencies of symptoms and signs are highly variable between centres, the clinical picture of the disease is similar [...] CSF indicating the stage of progression of the disease. Pruritus is...
ELF-MF exposure affects the robustness of epigenetic programming during granulopoiesis (Publications)
classified as "possibly carcinogenic" to humans on the grounds of an epidemiological association of ELF-MF exposure with an increased risk of childhood leukaemia. Yet, underlying mechanisms have remained [...] epigenetic code of genomes, which is well-known to be sensitive to environmental conditions and generally deranged in cancers, including leukaemia. We examined the potential of ELF-MF to influence key epigenetic [...] is, sensitive genome-wide profiling of multiple replicate experiments...
Spatial risk prediction and mapping of <em>Schistosoma mansoni</em> infections among schoolchildren living in western Côte d'Ivoire (Publications)
school prevalences of S. mansoni infection. The goodness of fit of different spatial models revealed that age, sex and socio-economic status had a stronger influence on infection prevalence than environmental [...] prevalence of S. mansoni was 38.9%, ranging from 0% to 89.3% among schools. Results showed that age, sex, the richest wealth quintile, elevation and rainfall explained the geographical variation of the school [...] The objectives of this study were (1) to examine risk factors for...
Sleepless night, the moon is bright: longitudinal study of lunar phase and sleep (Publications)
human physiology, behaviour and health. We examined the influence of moon phase on sleep duration in a secondary analysis of a feasibility study of mobile telephone base stations and sleep quality. We studied [...] studied 31 volunteers (18 women and 13 men, mean age 50 years) from a suburban area of Switzerland longitudinally over 6 weeks, including two full moons. Subjective sleep duration was calculated from sleep [...] (P < 0.001) and sleep duration decreased with age (P < 0.001). There was...
Muscle force up to 50% of maximum does not affect cutaneous silent periods in thenar muscles (Publications)
magnitude of EMG suppression were not influenced by volitional muscle contraction ranging from 10% to 50% of the maximum. In contrast, background EMG levels increased significantly with the amount of muscle [...] clinically easily applicable amounts of muscle force. SIGNIFICANCE: Non-dependence on the amount of volitional target muscle activation over a range from 10% to 50% of individual maximum force levels renders [...] (CSP) is a spinal inhibitory reflex mediated by A-delta fibers. The...
Effect of agricultural activities on prevalence rates, and clinical and presumptive malaria episodes in central Côte d'Ivoire (Publications)
dynamics of malaria episodes. A better understanding of local contextual determinants, including the effect of agricultural activities, will help to improve the local epidemiology and control of malaria [...] Agricultural activities, among other factors, can influence the transmission of malaria. In two villages of central Cote d'Ivoire (Tiemelekro and Zatta) with distinctively different agro-ecological ch [...] 2002 and 2005, which coincided with the interruption of irrigated rice farming in...
A validation of the religious and spiritual struggles scale among young people living with HIV in Zimbabwe: Mokken scale analysis and exploratory... (Publications)
convictions and practices can influence health- and treatment-seeking behavior, but only few measures of religiousness or spirituality have been validated and used outside of the US. The Religious and Spiritual [...] spirituality and has been validated mainly in different high-income contexts. The aim of this study was the validation of the RSS in the Zimbabwean context and among young people living with human immunodeficiency [...] The findings support the validity and relevance of the RSS and...
Land use regression modeling of outdoor noise exposure in informal settlements in Western Cape, South Africa (Publications)
5 dB(A)). Main predictors of the LUR model were related to road traffic and household density. Model performance was low (adjusted R2 = 0.130) suggesting that other influences than those represented in [...] in the geographic predictors are relevant for noise exposure. This is one of the few studies on the noise exposure situation in low- and middle-income countries. It demonstrates that noise exposure levels
Marginal bone loss one year after implantation: a systematic review of different loading protocols (Publications)
The aim of this study was to analyse the influence of different loading protocols on marginal bone loss (MBL). The outcomes of different implant loading protocols were assessed at 1year after implantation [...] highest for immediate non-occlusally loaded implants (1.37+/-0.5mm). The results of the meta-analysis showed an estimated mean MBL of 0.457mm (95% confidence interval (CI) 0.133-0.781) for immediate loading, [...] non-occlusal, early, and conventional loading. The search strategy resulted...