Factors influencing the work efficiency of district health managers in low-resource settings: a qualitative study in Ghana (Publications)
timely release of district funds. CONCLUSIONS: Filling District Health Management Team vacancies, developing leadership and management skills of district health managers, ensuring a better flow of district funds [...] management practices have detrimental effects. The aim of the present study was to identify factors contributing to inefficient management practices of district health managers and ways to improve their overall [...] were conducted with district health managers in three districts o...
Micro-scale investigation of intestinal schistosomiasis transmission on Ngamba and Kimi islands, Lake Victoria, Uganda (Publications)
A study to investigate the effect of environmental predictors on abundance of Biomphalaria, the intermediate host snails of Schistosoma mansoni, was carried out on two small islands in Lake Victoria, Uganda [...] documenting occurrence of Biomphalaria; other environmental and limnological conditions were also recorded, including gastropod community diversity. Snails were examined for shedding of schistosomes and emerging [...] analysis of Biomphalaria, snails from four populations from each...
Effective coverage in health systems: evolution of a concept (Publications)
and evolution of the concept of effective coverage metrics to illuminate potential improvements in coherence, terminology, application, and visualizations, based on which a combination of approaches appears [...] hypertension. Nevertheless, despite decades of application of effective coverage concepts, there is considerable variability in the terminology used and the choices of effectiveness decay steps included in the [...] need is a critical dimension of health system performance. Intervention...
Primary care case management of febrile children: insights from the ePOCT routine care cohort in Dar es Salaam, Tanzania (Publications)
care (PHC) case management of febrile children under-five in Dar es Salaam, and to identify areas for improving quality of care. Methods: We used data from the routine care arm of the ePOCT trial, including [...] points to challenges in using diagnostic test results, concerns regarding quality of antibiotic prescriptions, and frequent use of non-evidence-based complementary medicines in PHC in Tanzania. Larger studies [...] prospectively collected in all children. We used descriptive statistics...
Beijing sublineages of <em>Mycobacterium tuberculosis</em> differ in pathogenicity in the Guinea pig (Publications)
e from four of the five sublineages of lineage 2 in the guinea pig model and subjected these strains to comparative whole-genome sequencing. The results of these studies showed that all of the clinical [...] Beijing family of Mycobacterium tuberculosis strains is part of lineage 2 (also known as the East Asian lineage). In clinical studies, we have observed that isolates from the sublineage RD207 of lineage 2 were [...] strains were capable of growing and causing lung pathology in guinea pigs...
Measles, mumps and rubella: vaccination rate and seroprevalence in 8th grade students of 8 different sites in Switzerland 1995/96 (Publications)
and the Swiss cantons launched the MMR-vaccination campaign. Within the frame of the SCARPOL Study, the vaccination status of 649, 8th class students was registered and serum samples were collected. The [...] were determined. The vaccination rate was 84% for measles, 74% for mumps, and 62% for rubella, 55% of these children had been vaccinated with the combined vaccine MMR. The vaccination rate for the different [...] study areas varied from 70% to 95% for measles, 42% to 94% for mumps and 18%...
Quantitative structure: antiprotozoal activity relationships of sesquiterpene lactones (Publications)
properties. The observed variance in the biological data can be explained in terms of subtle variations in the relative influences of various molecular descriptors [...] Prompted by results of our previous studies where we found high activity of some sesquiterpene lactones (STLs) against Trypanosoma brucei rhodesiense (which causes East African sleeping sickness), we have [...] set of 40 STLs against T. brucei rhodesiense, T. cruzi, Leishmania donovani and Plasmodium falciparum. Furthermore,...
Factors influencing the work efficiency of district health managers in low-resource settings: a qualitative study in Ghana (Publications)
timely release of district funds. CONCLUSIONS: Filling District Health Management Team vacancies, developing leadership and management skills of district health managers, ensuring a better flow of district funds [...] management practices have detrimental effects. The aim of the present study was to identify factors contributing to inefficient management practices of district health managers and ways to improve their overall [...] were conducted with district health managers in three districts o...
Effects of smoking bans on passive smoking exposure at work and at home. The European Community Respiratory Health Survey (Publications)
ECHRS wave, the odds of passive smoking at work was markedly reduced after global smoking bans (OR=0.45, 95%CI 0.25-0.81), particularly among non-smokers, while the protective effect of global smoking bans [...] This longitudinal study investigated whether smoking bans influence passive smoking at work and/or at home in the same subjects. Passive smoking at work and/or at home was investigated in random population [...] workplaces were effective in reducing passive smoking at work in Europe....
Mapping and prediction of schistosomiasis in Nigeria using compiled survey data and Bayesian geospatial modelling (Publications)
database for the generation of point prevalence maps. This exercise revealed that the disease is endemic in 35 of the country's 36 states, including the federal capital territory of Abuja, and found in 462 [...] The estimated prevalence of S. haematobium, based on Bayesian geospatial predictive modelling with a set of bioclimatic variables, ranged from 0.2% to 75% with a mean prevalence of 23% for the country as [...] 462 unique locations out of 833 different survey locations. Schistosoma...