Acceptability and use of insecticide impregnated bednets in northern Ghana (Publications)
mosquito bites, seasonal factors, patterns of use, and questions of cost were key factors likely to influence the dissemination and effectiveness of bednets. Use of the bednets was highly seasonal. Almost [...] population of northern Ghana to identify factors influencing the acceptance and use of insecticide-impregnated bednets (IIBNs). A series of focus group discussions were conducted during 2 years of implementation [...] Provision of wider bednets, or the provision of plastic sheets with the...
Activity and structure relationship of acridine derivatives against African trypanosomes (Publications)
ketones of 9-thioacridines confirmed the tendency of increasing toxicity due to the derivatisation of the dialkylaminoalkyl side chain. Within the series of the 9-aminoacridines the elongation of the side [...] assay. After analysis of the IC50 and MIC values of the investigated acridines it was obvious that no new compound reached the level of the trypanocidal drugs in use (50 ng/ml). Most of the derivatives had [...] yl derivatives among the group of the 9-thioacridines were slightly more...
Metabonomic investigations of age- and batch-related variations in female NMRI mice using proton nuclear magnetic resonance spectroscopy (Publications)
and weight, and determined the influence of acclimatization on the metabolic profile of biofluids (urine, plasma, and faecal water). Differences in urinary concentrations of 3-ureidopropionate, 2-oxoisocaproate [...] information regarding baseline metabolism of this murine strain is relatively sparse. Using different batches of female NMRI mice, we assessed the stability of the metabolic phenotype with increasing age [...] for inclusion of an acclimatization period prior to starting an...
Sleep problems and work injury types: a study of 180 patients in a Swiss emergency department (Publications)
Knowledge about the influence of sleep problems on work injury patterns is limited. Therefore, the aim of this study was to identify potential associations between different types of work injuries and sleep [...] and various types of work injury. RESULTS: Each dimension of sleep problems - sleep quality, sleep duration and daytime sleepiness - was a significant risk factor for at least one type of work injury. The [...] study, 180 male and female patients with work injuries were recruited at...
Sex differentials in the uptake of antiretroviral treatment in Zambia (Publications)
This study explores socio-structural factors that influence uptake of antiretroviral treatment (ART) in Zambia and assess differences between men and women. We conducted a case-control study nested in [...] matched by place of residence. We performed a conditional logistic regression analysis using a discrete logistic model stratified by sex. Overall, a significantly larger proportion of men (32.7%) than [...] adjusted analysis suggests that HIV status disclosure affects uptake in both sexes but...
A systematic literature review of reported challenges in health care delivery to migrants and refugees in high-income countries - the 3C model (Publications)
information. RESULTS: Of 185 identified articles, 35 were included in the final analysis. We identified three main topics of challenges in health care delivery: communication, continuity of care and confidence [...] study included at least one of the three main topics and in 21/35 (60%) all three topics were mentioned. We further developed the 3C model and elaborated the interrelatedness of the three topics. Additional [...] and cultural aspects is important and further influences the 3C model....
Paternal pregnancy intention and breastfeeding duration: findings from the national survey of family growth (Publications)
benefits of breastfeeding, less than a fifth of American mothers breastfeed for the recommended duration. Paternal support plays a major role in maternal and child health outcomes; however, the influence of [...] fathers' pregnancy intention and breastfeeding duration. Methods Data from the 2011-2013 National Survey of Family Growth were analyzed using cross-sectional methodology. Women who were pregnant, never received
Relationship between <em>Mycobacterium tuberculosis</em> genotype and the clinical phenotype of pulmonary and meningeal tuberculosis (Publications)
presentation of meningitis by influencing the intracerebral inflammatory response. In addition, increased drug resistance among bacteria of the East Asian/Beijing lineage might influence the response to [...] We used large sequence polymorphisms to determine the genotypes of 397 isolates of Mycobacterium tuberculosis from human immunodeficiency virus-uninfected Vietnamese adults with pulmonary (n = 235) or [...] s. We compared the pretreatment radiographic appearances of pulmonary tuberculosis...
Evaluation of quinolone derivatives for antitrypanosomal activity (Publications)
effect of the drugs could not be confirmed in vivo, but the class of compound remains of interest for their mode of action, the low toxicity, pharmacological properties and the availability of a large [...] concentration of 100 &mgr;g/ml. In a structure activity relationship study, modification of the quinolones at position R1, R2, R3 and R8 did not influence trypanocidal activity. An exchange of the fluor at [...] an IC50 below 1 &mgr;g/ml and a selectivity index of more than 10 were chosen for...
Perceived environmental housing quality and wellbeing of movers (Publications)
Objective measures of wellbeing or environmental quality were not available. SETTING: North western region of Switzerland including the city of Basel. PARTICIPANTS: Random sample of 3870 subjects aged [...] OBJECTIVE: To examine whether changes in environmental housing quality influence the wellbeing of movers taking into account other dimensions of housing quality and sociodemographic factors. DESIGN: Cross sectional [...] and "noise from neighbours" (OR=1.32, 95% CI=1.07, 1.64). The...