Cultural context and impact of alcohol use in the Sundarban Delta, West Bengal, India (Publications)
clarifies features of alcohol availability, use, and acceptance in a neglected rural area of India. It illustrates the limitations of western clinical models of dependence and the importance of clarifying s [...] region influence changing patterns of acceptable and problem use of alcohol. Ethnographic methods included participant observation and focus group discussions. The qualitative data analysis of field notes [...] lacking. This community study aimed to clarify local patterns of alcohol use...
Activity and structure relationship of acridine derivatives against African trypanosomes (Publications)
ketones of 9-thioacridines confirmed the tendency of increasing toxicity due to the derivatisation of the dialkylaminoalkyl side chain. Within the series of the 9-aminoacridines the elongation of the side [...] assay. After analysis of the IC50 and MIC values of the investigated acridines it was obvious that no new compound reached the level of the trypanocidal drugs in use (50 ng/ml). Most of the derivatives had [...] yl derivatives among the group of the 9-thioacridines were slightly more...
Sleep problems and work injury types: a study of 180 patients in a Swiss emergency department (Publications)
Knowledge about the influence of sleep problems on work injury patterns is limited. Therefore, the aim of this study was to identify potential associations between different types of work injuries and sleep [...] and various types of work injury. RESULTS: Each dimension of sleep problems - sleep quality, sleep duration and daytime sleepiness - was a significant risk factor for at least one type of work injury. The [...] study, 180 male and female patients with work injuries were recruited at...
Sex differentials in the uptake of antiretroviral treatment in Zambia (Publications)
This study explores socio-structural factors that influence uptake of antiretroviral treatment (ART) in Zambia and assess differences between men and women. We conducted a case-control study nested in [...] matched by place of residence. We performed a conditional logistic regression analysis using a discrete logistic model stratified by sex. Overall, a significantly larger proportion of men (32.7%) than [...] adjusted analysis suggests that HIV status disclosure affects uptake in both sexes but...
What do district health managers in Ghana use their working time for? A case study of three districts (Publications)
practices of district health managers in Ghana. METHODS: All 21 district health managers working in three districts of the Eastern Region were included in the study and followed for a period of three months [...] conducted, covering 1182 person-days of observation. Total time use of the sample population was assessed as well as time use stratified by managerial position. Differences of time use over time were also evaluated [...] RESULTS: District health managers used most of their working time...
Social and cultural determinants of oral cholera vaccine uptake in Zanzibar (Publications)
examined the influence of local community views of cholera on oral cholera vaccine (OCV) uptake in a mass vaccination campaign in 2009 in peri-urban and rural areas of Zanzibar. It used data from interviews [...] determinants of anticipated OCV acceptance. OCV uptake was lower than the reported anticipated acceptance. Less than half of the 356 adult respondents (49.7%) drank the required two doses of OCV. Variables [...] l features of diarrheal illness that respondents identified with a cholera...
Evaluation of quinolone derivatives for antitrypanosomal activity (Publications)
effect of the drugs could not be confirmed in vivo, but the class of compound remains of interest for their mode of action, the low toxicity, pharmacological properties and the availability of a large [...] concentration of 100 &mgr;g/ml. In a structure activity relationship study, modification of the quinolones at position R1, R2, R3 and R8 did not influence trypanocidal activity. An exchange of the fluor at [...] an IC50 below 1 &mgr;g/ml and a selectivity index of more than 10 were chosen for...
Perceived environmental housing quality and wellbeing of movers (Publications)
Objective measures of wellbeing or environmental quality were not available. SETTING: North western region of Switzerland including the city of Basel. PARTICIPANTS: Random sample of 3870 subjects aged [...] OBJECTIVE: To examine whether changes in environmental housing quality influence the wellbeing of movers taking into account other dimensions of housing quality and sociodemographic factors. DESIGN: Cross sectional [...] and "noise from neighbours" (OR=1.32, 95% CI=1.07, 1.64). The...
Comparative testing of a miniature diffusion size classifier to assess airbone ultrafine particles under field conditions (Publications)
the development of cardiovascular and pulmonary diseases; thus, detection and quantification of these particles are important for evaluating their potential health hazards. As part of the UFP exposure [...] a highway. Measurements with miniDiSC and P-TRAK correlated well (correlation of r = 0.84) but average particle numbers of the miniDiSC were 30%âeuro"60% higher. This difference was significantly increased [...] dependent effect led to very similar results across all counters.We did not...
Acceptability and use of insecticide impregnated bednets in northern Ghana (Publications)
mosquito bites, seasonal factors, patterns of use, and questions of cost were key factors likely to influence the dissemination and effectiveness of bednets. Use of the bednets was highly seasonal. Almost [...] population of northern Ghana to identify factors influencing the acceptance and use of insecticide-impregnated bednets (IIBNs). A series of focus group discussions were conducted during 2 years of implementation [...] Provision of wider bednets, or the provision of plastic sheets with the...