The impact of health worker absenteeism on patient health care seeking behavior, testing and treatment: a longitudinal analysis in Uganda (Publications)
rates of health worker absenteeism at public sector health facilities, with most of the absenteeism occurring at lower level public health clinics. On average, no health worker was present in 42% of all [...] Absenteeism of frontline health workers in public sector facilities is widespread in low-income countries. There is little quantitative evidence on how health worker absenteeism influences patient treatment [...] 44-0.95) and receives malaria testing (OR = 0.73, 95% CI = 0.53-0.99) and...
Controlling schistosomiasis in Southeast Asia: a tale of two countries (Publications)
In addition, the lower rates of excreted eggs per gram of stool in the new endemic situation characterised by widespread, low-intensity infections influence the accuracy of prevalence assessments negatively [...] An overview of schistosomiasis control in the People's Republic of China and the Philippines is presented. Whilst the Chinese have managed to reduce the number of Schistosoma japonicum infections from [...] be seen in the context of the population growth, which approximately doubled the...
PASHA : Prevention and awareness in schools of HIV/AIDS : key documents and lessons learned from phase I (2003-2006) [CD-ROM] (Publications)
students. Prevention and Awareness at Schools of HIV/AIDS (PASHA) is a project of the Ministry of Education and Vocational Training (MOEVT) in the United Republic of Tanzania. It is funded by the German Federal [...] presents a window of hope for meaningful intervention, because most children and youth are still not infected by HIV. In addition, teachers have a strong influence on shaping decision making of their students [...] Development (BMZ) through the German Technical Cooperation (GTZ)....
Discovery and evaluation of thiazinoquinones as anti-protozoal agents (Publications)
167 muM). A series of C-7 amide and Delta2(3) analogues were prepared that explored the influence of lipophilicity and oxidation state on observed anti-protozoal activity and selectivity. Little variation [...] moderate growth inhibitor of Trypanosoma brucei rhodesiense (IC50 3.1 muM) and Plasmodium falciparum (K1 dual drug resistant strain) (IC50 3.3 muM) while exhibiting low levels of cytotoxicity (L6, IC50 167 [...] brucei rhodesiense compared to the natural product hit. A second series of...
Safety and immunogenicity of tetanus/diphtheria vaccination in patients with rheumatic diseases - a prospective multi-centre cohort study (Publications)
SpA/PsA, 39 vasculitis) and 253 HCs. Of the patients, 89% were on immunosuppressive/immunomodulatory medication. Three months post-vaccination 100% of HCs vs 98% of patients were protected against tetanus [...] aimed to assess the safety and immunogenicity of a diphtheria/tetanus vaccine booster dose in three different patient groups with rheumatic diseases on a variety of immunosuppressive/immunomodulatory medications [...] factor negatively influencing tetanus immunogenicity, whereas only MTX...
Response of cord blood cells to environmental, hereditary and perinatal factors: a prospective birth cohort study (Publications)
investigating the impact of individual risk factors on cord blood immune cell counts may be biased given that cord blood composition is influenced by a multitude of factors. The aim of this study was to co [...] in the composition of cord blood cells at birth, and it is important to adjust for all of these factors in cord blood studies. In particular, perinatal circumstances seem to influence immune balance, which [...] comprehensively investigate the relative impact of environmental, hereditary...
Effects of self-esteem and stress on self-assessed health: a Swiss study from adolescence to early adulthood (Publications)
PURPOSE: A large literature shows important effects of self-esteem and stress on mental and physical health in young adulthood. Negative life events are one type of stressor associated with poor health, but it [...] Education to Employment" (TREE) panel study, a nationally representative longitudinal survey of a cohort of Swiss young adults, using logistic regression analysis. The study includes eight waves over a [...] to their known influence on mental health, stress and self-esteem are...
Association of long-term exposure to traffic-related PM10 with heart rate variability and heart rate dynamics in healthy subjects (Publications)
cal evidence on the influence of long-term exposure to traffic-related particulate matter (TPM10) on heart rate variability (HRV) is weak. OBJECTIVE: To evaluate the association of long-term exposure (10years) [...] appeared to be more susceptible to the effects of TPM10. CONCLUSION: This study suggests that long-term exposure to TPM10 triggers adverse changes in the regulation of the cardiovascular system. These adverse [...] (10years) with TPM10 on the regulation of the autonomic...
Association between sleep disturbances and falls among the elderly: results from the German cooperative health research in the region of Augsburg-age... (Publications)
population while considering the influence of age and dizziness. METHODS: Data were derived from the population-based cross-sectional KORA (Cooperative Health Research in the Region of Augsburg)-Age study, whereby [...] daytime sleepiness and falls in the fully-adjusted models, but the odds of falls in the previous year in individuals older than the age of 75years were significantly higher for individuals with difficulty falling [...] in multivariable analyses when stratified by dizziness, sleep...
Radioiodine therapy in hyperthyroidism: inverse correlation of pretherapeutic iodine uptake level and post-therapeutic outcome (Publications)
controversial and the correlation of pretherapeutic RAI uptake level and outcome of RAI therapy has not yet been quantified. The aim of this study was to analyze the influence of RAI uptake on the outcome after [...] treatment was defined as loss of hyperthyroidism 18 months after radioiodine therapy. Logistic regression was used to assess the relation between the maximum iodine uptake and the rate of success and hypothyroidism