Evaluation of a urogenital schistosomiasis behavioural intervention among students from rural schools in Unguja and Pemba islands, Zanzibar (Publications)
school-aged children, those at greatest risk for urogenital schistosomiasis. We assessed the influence of a HEBC intervention, guided by the Health Belief model, among rural schoolchildren on Pemba and Unguja islands [...] Urogenital schistosomiasis is a common experience among children in Zanzibar. There is a paucity of behavioural science-based, health education, and behaviour change (HEBC) interventions for school-aged [...] students that were exposed or not exposed to the HEBC intervention...
Gender differences in the provision of intensive care: a Bayesian approach (Publications)
whether management and outcomes of critically ill patients differ between men and women. We sought to assess the influence of age, sex and diagnoses on the probability of intensive care provision in critically [...] 012]). CONCLUSION: In the care of the critically ill, our study suggests that women are less likely to receive ICU treatment regardless of disease severity. Underuse of ICU care was most prominent in younger [...] neurovascular patients in a large nationwide cohort in Switzerland....
Effect of mutation and genetic background on drug resistance in <em>Mycobacterium tuberculosis</em> (Publications)
002). We found that the genetic strain background influences the level of isoniazid resistance conveyed by particular mutations (interaction tests of drug resistance mutations across all lineages; P < [...] determined quantitative drug resistance levels of first-line drugs by using Bactec MGIT-960 and drug resistance genotypes by sequencing the hot-spot regions of the relevant genes. We determined recent tr [...] Bacterial factors may contribute to the global emergence and spread of...
Malaria knowledge and long-lasting insecticidal net use in rural communities of central Côte d'Ivoire (Publications)
was to determine factors that influence the use of long-lasting insecticidal nets (LLINs) in three rural communities of Cote d'Ivoire, two of which benefited from recent interventions. METHODS: The study [...] analysis was used to calculate the SEP of households by means of a list of household assets ownership. The concentration index was used to assess the direction of the association between SEP and a given [...] effectiveness of malaria control interventions, it is essential to deepen the...
Factors influencing the pattern of imported malaria (Publications)
incomplete because of underreporting and lack of homogeneity. These facts and the complexity of factors influencing the transmission of malaria render their interpretation difficult. The relevance of various factors [...] reported to the Federal Office of Public Health of Switzerland were analyzed. The reciprocal impact on data interpretation with regard to Plasmodium species, chemoprophylaxis, onset of first symptoms after return [...] duration of stay, nationality groups, and fatal outcome was...
Comparison of responses to an asthma symptom questionnaire (ISAAC core questions) completed by adolescents and their parents (Publications)
The primary objective of the study was to determine the impact of the identity of the respondent (parents versus adolescents) on prevalence estimates of asthma symptoms in Swiss adolescents. In addition [...] when a family history of asthma was recorded, when the adolescent was a non-smoker, and when the parental education was high. We conclude that the higher reporting of prevalence rates of current asthma symptoms [...] alone. The level of agreement between parental and self-completed...
Cystic fibrosis related diabetes is not associated with maximal aerobic exercise capacity in cystic fibrosis: a cross-sectional analysis of an... (Publications)
and without cystic fibrosis (CF) related diabetes (CFRD). However, none of the studies controlled for the potential influence of physical activity on VO2peak. We investigated associations between CFRD [...] 4 h per week of vigorous physical activity were used for this project. Multivariable models were computed to study associations between CFRD and VO2peak (mL.min(-1)) adjusting for a set of pre-defined [...] predicted). In the final multivariable model, all pre-defined covariates were...
Long-term air pollution exposure and COVID-19 case-severity: an analysis of individual-level data from Switzerland (Publications)
entire study period. Our findings suggest that the burden of air pollution increased the risks of COVID-19 in Switzerland during the first wave of the pandemic, but not during the second wave, when the national [...] addition, the majority of the studies used an ecological study design and were applied in regions with rather high air pollution levels. Here, we study the differential effects of long-term exposure to [...] individual-level analyses using data covering the first two major waves of...
Gender differences in the provision of intensive care: a Bayesian approach (Publications)
whether management and outcomes of critically ill patients differ between men and women. We sought to assess the influence of age, sex and diagnoses on the probability of intensive care provision in critically [...] 012]). CONCLUSION: In the care of the critically ill, our study suggests that women are less likely to receive ICU treatment regardless of disease severity. Underuse of ICU care was most prominent in younger [...] neurovascular patients in a large nationwide cohort in Switzerland....
Informed consent approaches for clinical trial participation of infants with minor parents in sub-Saharan Africa: a systematic review (Publications)
for children of minor parents participating in clinical trials. In countries with high rates of underage mothers, such as in sub-Saharan Africa, this lack of guidance may affect the rights of potential [...] paediatric participants already bearing increased vulnerability. It can also influence the recruitment and generalizability of the research. We provide evidence and discuss informed consent management in [...] minor" status lacked evidence in the context of research. National laws on...