Gene-environment interaction for childhood asthma and exposure to farming in Central Europe (Publications)
contact with cows and straw, or consumption of raw farm milk. CONCLUSION: Common genetic polymorphisms are unlikely to moderate the protective influence of the farming environment on childhood asthma and [...] from 4 rural regions of Central Europe. We also tested selectively for interactions between farm exposures and 7 SNPs that emerged as genome-wide significant in a large meta-analysis of childhood asthma and [...] and atopy, but rarer variants, particularly of the glutamate receptor,...
Carotid artery intima-media thickness in college students: race/ethnicity matters (Publications)
were recruited as part of a study to characterize determinants of atherogenesis. Students were eligible if they were lifetime non-smokers, lived in the United States since six months of age, and attended high [...] RESULTS: In models adjusted for common cardiovascular risk factors, sex exhibited the strongest influence on CIMT, with men having 15.4mum larger CIMT compared to women (95%CI 6.6, 24.2). Race/ethnicity
Carotid artery intima-media thickness in college students: race/ethnicity matters (Publications)
were recruited as part of a study to characterize determinants of atherogenesis. Students were eligible if they were lifetime non-smokers, lived in the United States since six months of age, and attended high [...] RESULTS: In models adjusted for common cardiovascular risk factors, sex exhibited the strongest influence on CIMT, with men having 15.4mum larger CIMT compared to women (95%CI 6.6, 24.2). Race/ethnicity
ProCOC: the prostate cancer outcomes cohort study (Publications)
development of prognostic biomarkers that indicate the future course of the illness is a promising approach with potential and the focus of much attention. These questions can be addressed in the context of a cohort [...] treatment for setup of a bio-bank. Assessment of these data and samples in the follow up will be done during routine controls. Study duration will be at least ten years. Influence of treatment on morbidity [...] canton of Zurich, Switzerland. We will include patients with newly...
ProCOC: the prostate cancer outcomes cohort study (Publications)
development of prognostic biomarkers that indicate the future course of the illness is a promising approach with potential and the focus of much attention. These questions can be addressed in the context of a cohort [...] treatment for setup of a bio-bank. Assessment of these data and samples in the follow up will be done during routine controls. Study duration will be at least ten years. Influence of treatment on morbidity [...] canton of Zurich, Switzerland. We will include patients with newly...
Mixed Th1 and Th2 <em>Mycobacterium tuberculosis</em>-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania (Publications)
functional profile of TB patients from Tanzania are primarily composed of polyfunctional Th1 and Th2 cells, associated with increased expression of Gata-3 and reduced expression of T-bet in memory CD4 [...] co-endemic in several regions of the world. We therefore hypothesized that helminth infection may influence Mtb-specific T-cell immune responses. We evaluated the cytokine profile of Mtb-specific T cells in [...] inflammation and elevated serum levels of type I IFNs. Of note, the proportion o...
Mixed Th1 and Th2 <em>Mycobacterium tuberculosis</em>-specific CD4 T cell responses in patients with active pulmonary tuberculosis from Tanzania (Publications)
functional profile of TB patients from Tanzania are primarily composed of polyfunctional Th1 and Th2 cells, associated with increased expression of Gata-3 and reduced expression of T-bet in memory CD4 [...] co-endemic in several regions of the world. We therefore hypothesized that helminth infection may influence Mtb-specific T-cell immune responses. We evaluated the cytokine profile of Mtb-specific T cells in [...] inflammation and elevated serum levels of type I IFNs. Of note, the proportion o...
Nutzen Behandlungsempfehlungen in psychiatrischen versicherungsrechtlichen Gutachten?[Treatment Recommendations in Psychiatric Disability Insurance... (Publications)
complied with in only 43 % of the cases; the recommended psychotherapy in only 9 % of the cases; and recommended in-patient treatment at a psychiatric hospital in only 14 % of the cases. During the time [...] number of people drawing a pension - especially for psychiatric reasons - from Switzerland's Federal Disability Insurance ("IV") has been steadily climbing. As we have revealed in earlier studies of persons [...] got a psychiatric expertise in 2004 at the Psychiatric Outpatient Department,...
Bone mineral density and its determinants in men with opioid dependence (Publications)
Data on the influence of opioid substitution therapy (OST) on skeletal health in men is limited. This cross-sectional study aimed to determine the prevalence of low bone mass in male drug users and to [...] buprenorphine (6 %). Overall, 74.3 % of men had low bone mass, with comparable bone mass irrespective of OST type. In older men (> /=40 years, n = 106), 29.2 % of individuals were osteoporotic (mean T-score [...] opioid maintenance therapy followed in the Center of Addiction Medicine in...
Nutzen Behandlungsempfehlungen in psychiatrischen versicherungsrechtlichen Gutachten?[Treatment Recommendations in Psychiatric Disability Insurance... (Publications)
complied with in only 43 % of the cases; the recommended psychotherapy in only 9 % of the cases; and recommended in-patient treatment at a psychiatric hospital in only 14 % of the cases. During the time [...] number of people drawing a pension - especially for psychiatric reasons - from Switzerland's Federal Disability Insurance ("IV") has been steadily climbing. As we have revealed in earlier studies of persons [...] got a psychiatric expertise in 2004 at the Psychiatric Outpatient Department,...