Effect of single nucleotide polymorphisms in cytochrome P450 isoenzyme and N-acetyltransferase-2 genes on the metabolism of artemisinin-based... (Publications)
The pharmacogenetics of antimalarials is poorly known, although its application might be critical to optimize treatment. This population pharmacokinetic-pharmacogenetic study aimed at assessing the ef
Synthesis and structure-activity relationships of new quinolone-type molecules against <em>Trypanosoma brucei</em> (Publications)
Human African trypanosomiasis (HAT) or sleeping sickness is caused by two subspecies of Trypanosoma brucei , Trypanosoma brucei gambiense , and Trypanosoma brucei rhodesiense and is one of Africa's ol
Consistently high estimates for the proportion of human exposure to malaria vector populations occurring indoors in rural Africa (Publications)
BACKGROUND: Insecticide-treated nets (ITNs) and indoor residual spraying (IRS) are highly effective tools for controlling malaria transmission in Africa because the most important vectors, from the An
Evaluation of the discriminatory power of variable number tandem repeat (VNTR) typing of <em>Mycobacterium bovis</em> strains (Publications)
The discriminatory power of variable number tandem repeat (VNTR) typing based on 16 known loci (12 MIRUs, 3 ETRs and VNTR 3232) was assessed for Mycobacterium bovis strains collected sequentially at t
Current status of schistosomiasis and soil-transmitted helminthiasis in Beyla and Macenta Prefectures, Forest Guinea (Publications)
A cross-sectional survey was undertaken in children aged 9-14 years in Beyla and Macenta Prefectures, Forest Guinea. Stool samples were examined by Kato-Katz and urine samples were examined by the cen
Characterization of invasive and colonizing isolates of <em>Streptococcus agalactiae</em> in East African adults (Publications)
95 colonizing and 74 invasive Streptococcus agalactiae isolates from Kenyan adults were characterized using capsular serotyping and multilocus sequence typing. 22 sequence types clustering into five c