Dicationic near-linear biphenyl benzimidazole derivatives as DNA-targeted antiprotozoal agents (Publications)
A series of near-linear biphenyl benzimidazole diamidines 5a-h were synthesized from their respective diamidoximes (4a-h), through the bis-O-acetoxyamidoxime, followed by hydrogenation in glacial acet
Association of daily physical activity volume and intensity with COPD severity (Publications)
PURPOSE: The purpose of this study was to assess whether daily walking activity is indicative of disease severity in patients with COPD. METHODS: Daily activity was measured by accelerometry in 107 CO
Treatment of breast cancer in the elderly: a prospective, population-based Swiss study (Publications)
Objectives: The primary objective of this population-based study is to describe the patterns of care of elderly patients with breast cancer (BC), and evaluate potential causative factors for the decre
Reference values for methacholine reactivity (SAPALDIA study) (Publications)
BACKGROUND: : The distribution of airway responsiveness in a general population of non-smokers without respiratory symptoms has not been established, limiting its use in clinical and epidemiological p
Use of transition probabilities to estimate the effect of smoking on the duration of episodes of respiratory symptoms in diary data: the Swiss Study... (Publications)
Incompletely documented symptom episodes pose methodological problems in the analysis of diary data. The aim of this study was to develop a method of estimating the average durations of symptomatic an
Selection bias of elderly patients with chronic angina referred for catheterization (Publications)
BACKGROUND: Registry patients are generally older and more sick than patients enrolled in trials questioning the generalizability of trial results. We assessed whether such a selection bias also exist
Home outdoor NO2 and new onset of self-reported asthma in adults (Publications)
BACKGROUND: Few studies have investigated new onset of asthma in adults in relation to air pollution. The aim of this study is to investigate the association between modeled background levels of traff
Association between modelled traffic-related air pollution and asthma score in the ECRHS (Publications)
The aim of our analysis was to study the association between air pollution and asthma among adults. For this goal, a previously developed "asthma score" was used. Persons aged 25-44 yrs were randomly