A ring-closing metathesis (RCM)-based approach to mycolactones A/B (Publications)
The total synthesis of the mycobacterial toxins mycolactones A/B (1 a/b) has been accomplished based on a strategy built around the construction of the mycolactone core through ring-closing metathesis
Humoral immune responses during a malaria vaccine trial in Tanzanian infants (Publications)
The development of a malaria vaccine is a priority for improved and sustained malaria control. Optimal use of a vaccine in Africa will only be achieved if it can be delivered through the Expanded Prog
Trypanosoma (Megatrypanum) incertum from <em>Pipistrellus pipistrellus</em>: development and transmission by cimicid bugs (Publications)
Trypanosoma (Megatrypanum) incertum Pittaluga 1905 was found in 33 out of 206 Pipistrellus pipistrellus caught at various sites in Britain. The trypanosome is described from blood smears. Development
Measurements of particle number and mass concentrations and size distributions in a tunnel environment (Publications)
Particulate matter emissions were measured in two bores of the Caldecott Tunnel in Northern California during August and September 2004. One bore (Bore 1) is open to both heavy- and light-duty vehicle
Comparative cost models of a liquid nitrogen vapor phase (LNVP) cold chain-distributed cryopreserved malaria vaccine vs. a conventional vaccine (Publications)
Typically, vaccines distributed through the Expanded Program on Immunization (EPI) use a 2-8°C cold chain with 4-5 stops. The PfSPZ vaccine comprises whole live-attenuated cryopreserved sporozoites st
Prospective study of a serogroup X <em>Neisseria meningitidis </em>outbreak in northern Ghana (Publications)
After an epidemic of serogroup A meningococcal meningitis in northern Ghana, a gradual disappearance of the epidemic strain was observed in a series of five 6-month carriage surveys of 37 randomly sel
Randomized double-blind controlled Phase I/IIa trial to assess the efficacy of malaria vaccine PfCS102 to protect against challenge with <em>P.... (Publications)
The aim of this Phase I/IIa double-blind controlled trial was to test the efficacy of the sporozoite-based malaria vaccine PfCS 282-383 (PfCS102) to protect against Plasmodium falciparum parasitaemia.
Increased incidence of Guillain-Barré syndrome after surgery (Publications)
BACKGROUND AND PURPOSE: Antecedent surgery has been described to trigger Guillain/x96Barre syndrome (GBS), but its evidence is poor and based on case reports only. METHODS: We performed a retrospectiv