One-hour rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T (Publications)
BACKGROUND High-sensitivity cardiac troponin (hs-cTn) assays seem to improve the early diagnosis of acute myocardial infarction (AMI), but it is unknown how to best use them in clinical practice. Our
Synthesis and antitrypanosomal evaluation of derivatives of N-benzyl-1,2-dihydroquinolin-6-ols: effect of core substitutions and salt formation (Publications)
Analogs of the trypanocidal lead compound 1-benzyl-1,2-dihydro-2,2,4-trimethylquinolin-6-yl acetate were prepared to extend the structure-activity relationship in this series of molecules, improve the
A Bayesian approach to estimate the age-specific prevalence of <em>Schistosoma mansoni</em> and implications for schistosomiasis control (Publications)
Models that accurately estimate the age-specific infection prevalence of Schistosoma mansoni can be useful for schistosomiasis control programmes, particularly with regard to whether mass drug adminis
Increased and expedited case detection by Xpert MTB/RIF assay in childhood tuberculosis: a prospective cohort study (Publications)
Background. Diagnosis and timely treatment of tuberculosis in children is hampered by the absence of fast and reliable tests, especially in the era of human immunodeficiency virus (HIV). The aim of th
The <em>Plasmodium falciparum</em> family of Rab GTPases (Publications)
Rab GTPases are key regulators of vesicular traffic in eukaryotic cells. Here we sought a global characterization and description of the Plasmodium falciparum family of Rab GTPases. We used a combinat