Determinants of time from HIV infection to linkage-to-care in rural KwaZulu-Natal, South Africa (Publications)
OBJECTIVE: To estimate time from HIV infection to linkage-to-care and its determinants. Linkage-to-care is usually assessed using the date of HIV diagnosis as the starting point for exposure time. How
Clinical markers of asthma and IgE assessed in parents before conception predicts asthma and hay fever in the offspring (Publications)
BACKGROUND: Mice models suggest epigenetic inheritance induced by parental allergic disease activity. However, we know little of how parental disease activity before conception influences offspring's
Malaria intervention scale-up in Africa: effectiveness predictions for health programme planning tools, based on dynamic transmission modelling (Publications)
BACKGROUND: Scale-up of malaria prevention and treatment needs to continue to further important gains made in the past decade, but national strategies and budget allocations are not always evidence-ba
Gaining and sustaining schistosomiasis control: study protocol and baseline data prior to different treatment strategies in five African countries (Publications)
BACKGROUND: The Schistosomiasis Consortium for Operational Research and Evaluation (SCORE) was established in 2008 to answer strategic questions about schistosomiasis control. For programme managers,
A systematic review of supportive supervision as a strategy to improve primary healthcare services in sub-Saharan Africa (Publications)
BACKGROUND: It may be assumed that supportive supervision effectively builds capacity, improves the quality of care provided by frontline health workers, and positively impacts clinical outcomes. Evid
Applied statistical training to strengthen analysis and health research capacity in Rwanda (Publications)
BACKGROUND: To guide efficient investment of limited health resources in sub-Saharan Africa, local researchers need to be involved in, and guide, health system and policy research. While extensive sur
Catalyzing the scale-up of community-based primary healthcare in a rural impoverished region of northern Ghana (Publications)
Ghana's Community-based Health Planning and Services (CHPS) initiative develops accessible healthcare with participatory community support, using strategies developed and tested by a project of the Na
The burden of leprosy in Cameroon: fifteen years into the post-elimination era (Publications)
BACKGROUND: Cameroon achieved the elimination target of leprosy in 2000, and has maintained this status ever since. However, a number of health districts in the country continue to report significant
2-Octadecynoic acid as a dual life stage inhibitor of <em>Plasmodium</em> infections and plasmodial FAS-II enzymes (Publications)
The malaria parasite Plasmodium goes through two life stages in the human host, a non-symptomatic liver stage (LS) followed by a blood stage with all clinical manifestation of the disease. In this stu
