2,4-diaminothienopyrimidines as orally active antimalarial agents (Publications)
A novel series of 2,4-diaminothienopyrimidines with potential as antimalarials was identified from whole-cell high-throughput screening of a SoftFocus ion channel library. Synthesis and structure-acti
<em>Paragonimus paishuihoensis</em> metacercariae in freshwater crabs, <em>Potamon lipkei</em>, in Vientiane Province, Lao PDR (Publications)
Among Paragonimus species, P. paishuihoensis is one of the most mysterious and poorly understood species. Metacercariae are characterized by having a unique dendritically branched excretory bladder. H
<em>In vitro</em> efficacy of dicationic compounds and mefloquine enantiomers against <em>Echinococcus multilocularis</em> metacestodes (Publications)
The current chemotherapy of alveolar echinococcosis (AE) is based on benzimidazoles such as albendazole and has been shown to be parasitostatic rather than parasiticidal, requiring lifelong duration.
Effect of sampling and diagnostic effort on the assessment of schistosomiasis and soil-transmitted helminthiasis and drug efficacy: a meta-analysis of... (Publications)
SUMMARY It is generally recommended to perform multiple stool examinations in order to improve the diagnostic accuracy when assessing the impact of mass drug administration programmes to control human
Occupational exposures and uncontrolled adult-onset asthma in the European Community Respiratory Health Survey II (Publications)
Occupational exposure is a well-recognised modifiable risk factor for asthma, but the relationship between occupational exposure and asthma control has not been studied. We aimed to study this associa
Recombinant expression of trypanosome surface glycoproteins in <em>Pichia pastoris</em> for the diagnosis of <em>Trypanosoma evansi</em> infection (Publications)
Serodiagnosis of surra, which causes vast economic losses in livestock, is still based on native antigens purified from bloodstream form Trypanosoma (T.) evansi grown in rodents. To avoid the use of l
Role of highway traffic on spatial and temporal distributions of air pollutants in a Swiss alpine valley (Publications)
Traffic-related air pollutants show high spatial variability near roads, posing a challenge to adequately assess exposures. Recent modeling approaches (e.g. dispersion models, land-use regression (LUR