Evolution of two distinct phylogenetic lineages of the emerging human pathogen <em>Mycobacterium ulcerans</em> (Publications)
ABSTRACT: BACKGROUND: Comparative genomics has greatly improved our understanding of the evolution of pathogenic mycobacteria such as Mycobacterium tuberculosis. Here we have used data from a genome m
Simplifying paediatric immunization with a fully liquid DTP-HepB-Hib combination vaccine: evidence from a comparative time-motion study in India (Publications)
An observational time-motion study investigated logistic, programmatic and safety-related advantages and limits in the delivery of a fully liquid DTP-HepB-Hib combination vaccine versus a lyophilized
Strategies to improve the medical device life cycle in Mexico (Publications)
OBJECTIVE: To analyze the role of stakeholders to three alternative strategies to improve processes and practices regarding the regulation, assessment, and management of orthopaedic medical devices in
A prospective, open-label, randomized trial of doxycycline versus azithromycin for the treatment of uncomplicated murine typhus (Publications)
Background: Murine typhus, or infection with Rickettsia typhi, is a global but neglected disease without randomised clinical trials to guide antibiotic therapy. Doxycycline is commonly used but withou
Xpert MTB/RIF Ultra assay for the diagnosis of pulmonary tuberculosis in children: a multicentre comparative accuracy study (Publications)
OBJECTIVES: We evaluated the diagnostic performance of the novel next-generation Xpert MTB/RIF Ultra (Xpert Ultra) in comparison to Xpert MTB/RIF (Xpert) assay for the detection of paediatric pulmonar
Development and validation of a LC-MS/MS method for ivermectin quantification in dried blood spots: application to a pharmacokinetic study in... (Publications)
Ivermectin serves as a good addition to the small group of medications for soil-transmitted helminths, particularly against Trichuris trichiura infections. So far, ivermectin has been poorly character
N-oxide alkaloids from <em>Crinum amabile</em> (Amaryllidaceae) (Publications)
Natural products play an important role in the development of new drugs. In this context, the Amaryllidaceae alkaloids have attracted considerable attention in view of their unique structural features