Assessment of ultra-sensitive malaria diagnosis versus standard molecular diagnostics for malaria elimination: an in-depth molecular community... (Publications)
BACKGROUND: Submicroscopic malaria infections contribute to transmission in exposed populations but their extent is underestimated even by standard molecular diagnostics. Sophisticated sampling and ul
Meta-analysis of exome array data identifies six novel genetic loci for lung function (Publications)
Background: Over 90 regions of the genome have been associated with lung function to date, many of which have also been implicated in chronic obstructive pulmonary disease. Methods: We carried out met
The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing (Publications)
Kinetoplastid parasites-trypanosomes and leishmanias-infect millions of humans and cause economically devastating diseases of livestock, and the few existing drugs have serious deficiencies. Benzoxabo
Transmission of hepatitis B and D viruses in an African rural community (Publications)
According to the World Health Organization (WHO), an estimated 257 million people worldwide are chronically infected with hepatitis B virus (HBV), with approximately 15 million of them being coinfecte
Connaissances-attitudes-pratiques des agents de santé humaine et animale sur la rage au Tchad (Publications)
Introduction: Rabies, an infectious disease mainly transmitted by dog bites, is fatal due to lack of appropriate knowledge-attitudes-practices (KAP). The KAP of healthcare providers are particularly i
Development and evaluation of a multiplex quantitative real-time polymerase chain reaction for hookworm species in human stool (Publications)
Hookworm disease caused by Necator americanus, Ancylostoma duodenale, and Ancylostoma ceylanicum affects half a billion people worldwide. The prevalence and intensity of infection of individual hookwo
The prevalence of brucellosis and bovine tuberculosis in ruminants in Sidi Kacem Province, Morocco (Publications)
Bovine tuberculosis (BTB) and brucellosis are major endemic zoonoses in ruminants in Morocco that impact on both animal and human health. This study presents an assessment of the epidemiological and s
The Comparative Effectiveness of Innovative Treatments for Cancer (CEIT-Cancer) project: rationale and design of the database and the collection of... (Publications)
BACKGROUND: The available evidence on the benefits and harms of novel drugs and therapeutic biologics at the time of approval is reported in publicly available documents provided by the US Food and Dr
Effects of vancomycin and ciprofloxacin on the NMRI mouse metabolism (Publications)
The reduction in gut microbiota diversity is associated with a range of human diseases. Overuse of antibiotics has been associated with a diminished gut-microbial diversity in humans, and may promote