Epigenome-wide association study of lung function level and its change (Publications)
Previous reports link differential DNA methylation (DNAme) to environmental exposures which are associated with lung function. Direct evidence on lung function DNAme is however limited. We undertook a
Single pivotal trials with few corroborating characteristics were used for FDA approval of cancer therapies (Publications)
INTRODUCTION: Novel cancer therapies are often approved with evidence from a single pivotal trial alone. There are concerns about the credibility of this evidence. Higher validity may be indicated by
RTS,S malaria vaccine pilot studies: addressing the human realities in large-scale clinical trials (Publications)
A malaria vaccine as part of the integrated malaria control and elimination efforts will have a major impact on public health in sub-Sahara Africa. The first malaria vaccine, RTS,S, now enters pilot i
Linking human behaviours and malaria vector biting risk in south-eastern Tanzania (Publications)
To accelerate malaria elimination in areas where core interventions such as insecticide-treated nets (ITNs) are already widely used, it is crucial to consider additional factors associated with persis
Genetic risk scores do not improve asthma prediction in childhood (Publications)
CAPSULE SUMMARY: Genetic risk scores have no added value above familial, perinatal and environmental risk factors in the first year of life to predict childhood asthma.
The feasibility and acceptability of collaborative learning in improving health worker performance on adolescent health: findings from implementation... (Publications)
BACKGROUND: Collaborative learning has been shown to be effective in improving health worker performance, but relatively little is known about the feasibility or acceptability of collaborative learnin