Chronic exposure to ambient ozone and lung function in young adults (Publications)
BACKGROUND: Tropospheric ozone (O3) is an oxidant, outdoor air pollutant. Chronic exposure has been associated with decreased lung function in children and adolescents. This study investigated the eff
Factors motivating individuals to take precautionary action for an expected earthquake in Istanbul (Publications)
Istanbul is expected to experience an earthquake in the near future, but individuals show limited interest in preparing for it. This study aims to identify the factors associated with taking action to
Synthesis and evaluation of beta-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis (Publications)
Several beta-carbolines including naturally occurring substances and their corresponding cationic derivatives were synthesized and evaluated for antimalarial (antiplasmodial) activity in vitro and in
Inhibition of <em>Plasmodium falciparum</em> fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids (Publications)
After the discovery of a potent natural flavonoid glucoside as a potent inhibitor of FabI, a large flavonoid library was screened against three important enzymes (i.e., FabG, FabZ, and FabI) involved
Synthesis and structure-activity analysis of new phosphonium salts with potent activity against African trypanosomes (Publications)
A series of 73 bisphosphonium salts and 10 monophosphonium salt derivatives were synthesized and tested in vitro against several wild type and resistant lines of Trypanosoma brucei (T. b. rhodesiense