Local heat application for the treatment of Buruli ulcer: results of a phase II open label single center non comparative clinical trial (Publications)
BACKGROUND: Buruli ulcer (BU) is a necrotising skin disease most prevalent among West African children. The causative organism, Mycobacterium ulcerans, is sensitive to temperatures above 37 degrees C.
Travellers' profile, travel patterns and vaccine practices - a 10-year prospective study in a Swiss Travel Clinic (Publications)
BACKGROUND: The travel clinic in Lausanne serves a catchment area of 700 000 of inhabitants and provides pre- and post-travel consultations. This study describes the profile of attendees before depart
Travel-related health risks in moderately and severely immunocompromised patients: a case-control study (Publications)
BACKGROUND: The number of immunocompromised persons travelling to tropical countries is increasing. The hypothesis is that this population is at increased risk of travel-related health problems but th
Evaluation of Xpert® MTB/RIF and Ustar EasyNATTM TB IAD for diagnosis of TB lymphadenitis of children in Tanzania (Publications)
BACKGROUND: Fine needle aspiration biopsy has become a standard approach for diagnosis of peripheral tuberculous lymphadenitis. The aim of this study was to compare the performance of Xpert MTB/RIF an
Efficacy, safety, and dose of pafuramidine, a new oral drug for treatment of first stage sleeping sickness, in a phase 2a clinical study and phase 2b... (Publications)
BACKGROUND: Sleeping sickness (human African trypanosomiasis [HAT]) is caused by protozoan parasites and characterized by a chronic progressive course, which may last up to several years before death.