Baseline health conditions in selected communities of northern Sierra Leone as revealed by the health impact assessment of a biofuel project (Publications)
BACKGROUND: As biofuel projects may be associated with positive and negative effects on people's health and wellbeing, a health impact assessment was performed for the Addax Bioenergy Sierra Leone (AB
Pyridyl benzamides as a novel class of potent inhibitors for the kinetoplastid <em>Trypanosoma brucei</em> (Publications)
A whole-organism screen of approximately 87000 compounds against Trypanosoma brucei brucei identified a number of promising compounds for medicinal chemistry optimization. One of these classes of comp
Heterochromatin protein 1 secures survival and transmission of malaria parasites (Publications)
Clonally variant expression of surface antigens allows the malaria parasite Plasmodium falciparum to evade immune recognition during blood stage infection and secure malaria transmission. We demonstra
Psychiatric disorders, suicidality, and personality among young men by sexual orientation (Publications)
Personality and its potential role in mediating risk of psychiatric disorders and suicidality are assessed by sexual orientation, using data collected among young Swiss men (n=5875) recruited while pr
<em>Plasmodium falciparum</em> and <em>Plasmodium vivax</em> genotypes and efficacy of intermittent preventive treatment in Papua New Guinea (Publications)
Intermittent preventive treatment of infants (IPTi) reduces early-childhood malaria-related morbidity. While genotypic drug resistance markers have proven useful in predicting the efficacy of antimala
<em>In vitro</em> and<em> In vivo</em> evaluation of 28DAP010, a novel diamidine for treatment of second-stage African sleeping sickness (Publications)
African sleeping sickness is a neglected tropical disease transmitted by tsetse flies. New and better drugs are still needed especially for its second stage, which is fatal if untreated. 28DAP010, a d
Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function (Publications)
Thymic stromal lymphopoietin (TSLP) is an interleukin (IL)-7-like cytokine, mainly expressed by epithelial cells, and key to the development of allergic responses. The well-documented involvement of T