An automated, interactive analysis system for ultrasound sequences of the common carotid artery (Publications)
Structural parameters of the common carotid artery (CCA) have shown to correlate with the risk of cardiovascular disease, but their precise measurement is challenging. We developed an automatic detect
Long-term ambient air pollution and respiratory symptoms in adults (SAPALDIA study) (Publications)
The association between long-term exposure to ambient air pollution and respiratory symptoms was investigated in a cross-sectional study in random population samples of adults (aged 18 to 60 yr, n = 9
Clinical diagnosis of current asthma: predictive value of respiratory symptoms in the SAPALDIA study. Swiss Study on Air Pollution and Lung Diseases... (Publications)
Bronchial asthma is a very common disease which often remains underdiagnosed. The aim of this study was to determine the predictive value of the most common respiratory symptoms and to explore the bes
Exposure to motor vehicle traffic and allergic sensitization. The Swiss Study on Air Pollution and Lung Diseases in Adults (SAPALDIA) Team (Publications)
We examined the association between the presence of an allergic sensitization and seasonal allergic diseases or symptoms and the exposure to road traffic in Basel, Switzerland. Traffic counts at the d
Effects of filter choice in GT3X accelerometer assessments of free-living activity (Publications)
PURPOSE: Actigraph accelerometers are widely used devices to objectively assess physical activity. The GT3X version has two filter options to be selected prior to data assessment (normal and low frequ
Predictors of methacholine responsiveness in a general population (Publications)
OBJECTIVE: Methacholine responsiveness is an end point widely used in epidemiologic studies of asthma. This study aims to quantify the relative importance of different predictors of responsiveness suc
Glutathione S-transferase polymorphisms, passive smoking, obesity, and heart rate variability in nonsmokers (Publications)
BACKGROUND: Disturbances of heart rate variability (HRV) may represent one pathway by which second-hand smoke (SHS) and air pollutants affect cardiovascular morbidity and mortality. The mechanisms are
Ten-year follow-up of cluster-based asthma phenotypes in adults: a pooled analysis of three cohorts (Publications)
Rationale: The temporal stability of adult asthma phenotypes identified using clustering methods has never been addressed. Longitudinal cluster-based methods may provide novel insights in the study of
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction (Publications)
RATIONALE: Genome-wide association studies (GWAS) have identified loci influencing lung function, but fewer genes influencing chronic obstructive pulmonary disease (COPD) are known. OBJECTIVES: Perfor