Clinical data combined with modelling and simulation indicate unchanged drug-drug interaction magnitudes in the elderly (Publications)
Age-related comorbidities and consequently polypharmacy are highly prevalent in the elderly, resulting in an increased risk for drug-drug interactions (DDIs). The effect of aging on DDI magnitudes is
Incidence of depression in relation to transportation noise exposure and noise annoyance in the SAPALDIA study (Publications)
Prospective evidence on the risk of depression in relation to transportation noise exposure and noise annoyance is limited and mixed. We aimed to investigate the associations of long-term exposure to
Comparative functional survival and equivalent annual cost of 3 long-lasting insecticidal net (LLIN) products in Tanzania: a randomised trial with... (Publications)
BACKGROUND: Two billion long-lasting insecticidal nets (LLINs) have been procured for malaria control. A functional LLIN is one that is present, is in good physical condition, and remains insecticidal
<em>Strongyloides stercoralis</em> prevalence and diagnostics in Vientiane, Lao People's Democratic Republic (Publications)
BACKGROUND: Despite the high prevalence of strongyloidiasis in the Laotian population, Laotian hospitals still lack diagnostic capacity to appropriately diagnose Strongyloides stercoralis infections.
Palladium-catalysed synthesis of arylnaphthoquinones as antiprotozoal and antimycobacterial agents (Publications)
Malaria and tuberculosis are still among the leading causes of death in low-income countries. The 1,4-naphthoquinone (NQ) scaffold can be found in a variety of anti-infective agents. Herein, we report
Financial costs of the Zanzibar elimination of schistosomiasis transmission project (Publications)
We estimated the financial costs of different interventions against urogenital schistosomiasis, implemented by the Zanzibar Elimination of Schistosomiasis Transmission (ZEST) project, on Pemba and Ung
Informed consent approaches for clinical trial participation of infants with minor parents in sub-Saharan Africa: a systematic review (Publications)
BACKGROUND: Regulations are vague regarding the appropriate decision-maker and authority to consent for children of minor parents participating in clinical trials. In countries with high rates of unde
(+/-)-<em>trans</em>-2-phenyl-2,3-dihydrobenzofurans as leishmanicidal agents: synthesis, <em>in vitro</em> evaluation and SAR analysis (Publications)
Leishmaniasis, a neglected tropical disease caused by parasites of the genus Leishmania, causes a serious burden of disease around the world, represents a threat to the life of millions of people, and
How does district health management emerge within a complex health system? Insights for capacity strengthening in Ghana (Publications)
Introduction: District health managers (DHMs) play a pivotal role in the operation of district health systems in low-and middle income countries, including Ghana. Their capacity is determined by their
