Emulator-based Bayesian optimization for efficient multi-objective calibration of an individual-based model of malaria (Publications)
Individual-based models have become important tools in the global battle against infectious diseases, yet model complexity can make calibration to biological and epidemiological data challenging. We p
Lived experiences and perceptions of childbirth among pastoralist women in north-eastern Ethiopia: a multimethod qualitative analysis to the WHO... (Publications)
Maternity should be a time of hope and joy. However, for women in pastoralist communities in Ethiopia, the reality of motherhood is often grim. This problem is creating striking disparities of skilled
Economic evaluation of disease elimination: an extension to the net-benefit framework and application to human African trypanosomiasis (Publications)
The global health community has earmarked a number of diseases for elimination or eradication, and these goals have often been praised on the premise of long-run cost savings. However, decision makers
Optimizing moxidectin dosing for <em>Strongyloides stercoralis</em> infections: insights from pharmacometric modeling (Publications)
Moxidectin is a frontrunner drug candidate in the treatment of strongyloidiasis. A dose of 8 mg is recommended to treat this indication, which shows a reasonably good efficacy and tolerability profile
Using observed incidence to calibrate the transmission level of a mathematical model for <em>Plasmodium vivax</em> dynamics including case management... (Publications)
In this work, we present a simple and flexible model for Plasmodium vivax dynamics which can be easily combined with routinely collected data on local and imported case counts to quantify transmission
Risk factors and spatial distribution of <em>Schistosoma mansoni </em>infection among preschool-aged children in Blapleu, Biankouma district, Western... (Publications)
Schistosoma mansoni infection is common among school-age children (SAC) in western Cote d'Ivoire. Little is known on the infection rate of preschool-aged children (PSAC) due to epidemiological data de
The 3-phosphoinositide-dependent protein kinase 1 is an essential upstream activator of protein kinase A in malaria parasites (Publications)
Cyclic adenosine monophosphate (cAMP)-dependent protein kinase A (PKA) signalling is essential for the proliferation of Plasmodium falciparum malaria blood stage parasites. The mechanisms regulating t
Vaccine hesitancy and its determinants – a way forward? (Publications)
The availability of highly effective SARS-CoV-2 vaccines brought about renewed hope worldwide to overcome the pandemic, becoming an integral part of public health measures. However, vaccine hesitance,
Seasonal variations in air concentrations of 27 organochlorine pesticides (OCPs) and 25 current-use pesticides (CUPs) across three agricultural areas... (Publications)
For decades pesticides have been used in agriculture, however, the occurrence of legacy organochlorine pesticides (OCPs) and current-use pesticides (CUPs) is poorly understood in Africa. This study in