Using and improving the PHISICC paper-based tools in the health facility laboratories: examples of Human Centered Design taking systems thinking into... (Publications)
BackgroundHealth workers in low- and middle-income countries are increasingly demanded to collect more and more data to report them to higher levels of the health information system (HIS), in detrimen
Exploring a tetrahydroquinoline antimalarial hit from the medicines for malaria pathogen box and the identification of its mode of resistance as... (Publications)
New antimalarial treatments with novel mechanism of action are needed to tackle Plasmodium falciparum infections that are resistant to first-line therapeutics. Here we report the exploration of MMV692
Co-infection of the four major <em>Plasmodium </em>species: effects on densities and gametocyte carriage (Publications)
BACKGROUND: Co-infection of the four major species of human malaria parasite Plasmodium falciparum (Pf), P. vivax (Pv), P. malariae (Pm), and P. ovale sp. (Po) is regularly observed, but there is limi
Modulation of host-parasite interactions with small molecules targeting <em>Schistosoma mansoni </em>microRNAs (Publications)
Parasites use different strategies of communication with their hosts. One communication channel that has been studied in recent years is the use of vesicle microRNAs to influence the host immune syste
The evolving SARS-CoV-2 epidemic in Africa: insights from rapidly expanding genomic surveillance (Publications)
Investment in SARS-CoV-2 sequencing in Africa over the past year has led to a major increase in the number of sequences generated, now exceeding 100,000 genomes, used to track the pandemic on the cont
Acceptability measures of water, sanitation and hygiene interventions in low- and middle-income countries, a systematic review (Publications)
BACKGROUND: Inadequate access to water, sanitation, and hygiene (WASH) is an environmental risk factor for poor health outcomes globally, particularly for children in low- and middle-income countries
COVID-19 vaccine booster strategies in light of emerging viral variants: frequency, timing, and target groups (Publications)
BACKGROUND: Vaccinations have reduced severe burden of COVID-19 and allowed for lifting of non-pharmaceutical interventions. However, with immunity waning alongside emergence of more transmissible var
Functional limitations 12 months after SARS-CoV-2 infection correlate with initial disease severity: an observational study of cardiopulmonary... (Publications)
BACKGROUND: Cardiopulmonary Exercise Testing (CPET) provides a comprehensive assessment of pulmonary, cardiovascular and musculosceletal function. Reduced CPET performance could be an indicator for ch
Pharmacokinetics of ascending doses of praziquantel in adults infected with <em>Opisthorchis felineus</em> in Western Siberia, Russian Federation (Publications)
Opisthorchiasis due to the liver fluke Opisthorchis felineus is highly prevalent in rural regions of Western Siberia, causing severe liver and bile duct maladies. Praziquantel administered as a three-