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1. New acyl derivatives of 3-aminofurazanes and their antiplasmodial activities (Publications)

   New acyl derivatives of 3-aminofurazanes and their antiplasmodial activities

   Relevanz:

   An N-acylated furazan-3-amine of a Medicines for Malaria Venture (MMV) project has shown activity against different strains of Plasmodium falciparum. Seventeen new derivatives were prepared and tested

2. Multiple air pollutant exposure and lung cancer in Tehran, Iran (Publications)

   Multiple air pollutant exposure and lung cancer in Tehran, Iran

   Relevanz:

   Lung cancer is the most rapidly increasing malignancy worldwide with an estimated 2.1 million cancer cases in the latest, 2018 World Health Organization (WHO) report. The objective of this study was t

3. 3-Hydroxy-propanamidines, a new class of orally active antimalarials targeting <em>Plasmodium falciparum</em> (Publications)

   3-Hydroxy-propanamidines, a new class of orally active antimalarials targeting <em>Plasmodium falciparum</em>

   Relevanz:

   3-Hydroxypropanamidines are a new promising class of highly active antiplasmodial agents. The most active compound 22 exhibited excellent antiplasmodial in vitro activity with nanomolar inhibition of

4. Urgent need to take action on reducing postoperative respiratory complications (Publications)

   Urgent need to take action on reducing postoperative respiratory complications

   Relevanz:

5. Melting the <em>eis</em>: non-detection of kanamycin resistance markers by routine diagnostic tests and identification of new <em>eis</em>-promoter... (Publications)

   Melting the <em>eis</em>: non-detection of kanamycin resistance markers by routine diagnostic tests and identification of new <em>eis</em>-promoter variants

   Relevanz:

   Eis-promoter mutations can confer reduced Mycobacterium tuberculosis kanamycin susceptibility. GenoType MTBDRsl, a widely used assay evaluating this region, wrongly classified 17/410 isolates as eis-p

6. The consequences of declining population access to insecticide-treated nets (ITNs) on net use patterns and physical degradation of nets after 22... (Publications)

   The consequences of declining population access to insecticide-treated nets (ITNs) on net use patterns and physical degradation of nets after 22 months of ownership

   Relevanz:

   BACKGROUND: As insecticide-treated nets (ITNs) wear out and are disposed, some household members are prioritized to use remaining ITNs. This study assessed how nets are allocated within households to

7. Spirombandakamine A3 and cyclombandakamines A8 and A9, polycyclic naphthylisoquinoline dimers, with antiprotozoal activity, from a Congolese... (Publications)

   Spirombandakamine A3 and cyclombandakamines A8 and A9, polycyclic naphthylisoquinoline dimers, with antiprotozoal activity, from a Congolese <em>Ancistrocladus</em> plant

   Relevanz:

   Spirombandakamine A3 (7) is only the third known naphthylisoquinoline dimer with a spiro-fused novel molecular framework and the first such representative to possess a relative trans-configuration at

8. Measuring early childhood development: considerations and evidence regarding the caregiver reported early development instruments (Publications)

   Measuring early childhood development: considerations and evidence regarding the caregiver reported early development instruments

   Relevanz:

   Reflecting a burgeoning political interest in supporting young children around the world, global demand for reliable, valid, and scalable assessments of early childhood development (ECD) is on the ris

9. The coexistence of asthma and COPD: risk factors, clinical history and lung function trajectories (Publications)

   The coexistence of asthma and COPD: risk factors, clinical history and lung function trajectories

   Relevanz:

   RATIONALE: Patients with concomitant features of asthma and chronic obstructive pulmonary disease (COPD) have a heavy disease burden. OBJECTIVES: Using data collected prospectively in the European Com

10. High burden of tuberculosis infection and disease among people receiving medication-assisted treatment for substance use disorder in Tanzania (Publications)

    High burden of tuberculosis infection and disease among people receiving medication-assisted treatment for substance use disorder in Tanzania

    Relevanz:

    OBJECTIVE: To determine the prevalence of tuberculosis (TB) disease and infection as well as incident TB disease among people who use drugs (PWUD) attending Medication Assisted Treatment (MAT) clinics