Vaccines against malaria: perspectives from Papua New Guinea (Publications)
Despite its small population and isolated location Papua New Guinea (PNG) with a malaria burden comparable to sub-Saharan Africa, its intense transmission of all four human Plasmodium species and an u
Cholesterol screening in childhood: results of a 9-year follow-up study in Swiss and Italian children in Switzerland (Publications)
Mass screening for blood cholesterol as part of routine preventive health care of children continues to be discussed in several countries. Results of longitudinal studies underline the importance of t
Imidazolopiperazines: lead optimization of the second-generation antimalarial agents (Publications)
On the basis of the initial success of optimization of a novel series of imidazolopiperazines, a second generation of compounds involving changes in the core piperazine ring was synthesized to improve
Association of early-life exposure to household gas appliances and indoor nitrogen dioxide with cognition and attention behavior in preschoolers (Publications)
The authors investigated the association of early-life exposure to indoor air pollution with neuropsychological development in preschoolers and assessed whether this association differs by glutathione
Use of B-type natriuretic peptide in the evaluation and management of acute dyspnea (Publications)
BACKGROUND: B-type natriuretic peptide levels are higher in patients with congestive heart failure than in patients with dyspnea from other causes. METHODS: We conducted a prospective, randomized, con
Chloroquine-astemizole hybrids with potent in vitro and in vivo antiplasmodial activity (Publications)
A dual activity, conjugated approach has been taken to form hybrid molecules of two known antimalarial drugs, chloroquine (CQ) and the non-sedating H1 antagonist astemizole. A variety of linkers were
