Limited genetic diversity of hepatitis B virus in the general population of the Offin River valley in Ghana (Publications)
countries, the other 33 formed a separate cluster distinguished by an intergroup mean distance of 1.5% from the pan-African HBV/E cluster. Successful implementation of HBV vaccination in the region was
Imported strongyloidosis: a longitudinal analysis of 31 cases (Publications)
reasons for diagnostic work-up were clinical symptoms in 84% and eosinophilia and screening in each of 22.5%. All patients had a history of travel or residence in endemic areas. Initial therapy was effective
Household survey of pesticide practice, deliberate self-harm and suicide in the Sundarban region of west Bengal, India (Publications)
about safe storage of pesticides. The pesticide-related annual DSH rate was 158.1 (95% CI 126.2-195.5), and for suicide it was 73.4 (95% CI 52.2-100.3) per 100,000. Unsafe pesticide practice and psychosocial
Novel 3-nitro-1H-1,2,4-triazole-based compounds as potential anti-Chagasic drugs: <em>in vivo</em> studies (Publications)
13 compounds demonstrated significant antichagasic activity when administered intraperitoneally for 5-10 days at relatively small doses. The best in vivo activity was demonstrated by amides and sulfonamide
<em>In silico</em> prediction and experimental evaluation of furanoheliangolide sesquiterpene lactones as potent agents against <em>Trypanosoma brucei... (Publications)
exceptionally high level of in vitro activity. Four representative compounds of this type, goyazensolide, 4,5-dihydro-2' ,3' -epoxy-15-deoxygoyazensolide, budlein A and 4,15-isoatriplicolide tiglate, were therefore
Schistosomiasis in European travelers and migrants: analysis of 14 years TropNet Surveillance Data (Publications)
Schistosoma mansoni was identified in 570 (39%) and Schistosoma haematobium in 318 (22%) cases; 57.5% of patients were symptomatic. Acute symptoms were reported in 27% of patients leading to earlier p
Common variants in Mendelian kidney disease genes and their association with renal function (Publications)
entries, corresponding to mutations in 258 genes. We interrogated common SNPs (minor allele frequency > 5%) within these genes for association with the estimated GFR in 74,354 European-ancestry participants
Land use regression models for alkylbenzenes in a Middle Eastern megacity: Tehran Study of Exposure Prediction for Environmental Health Research... (Publications)
a megacity. About 83% of Tehran's surface had benzene concentrations above air quality standard of 5 microg/m3 set by European Union and Iranian Government. Toluene was the predominant alkylbenzene and
Molecular basis for covalent inhibition of glyceraldehyde-3-phosphate dehydrogenase by a 2-phenoxy-1,4-naphthoquinone small molecule (Publications)
covalent inhibition is not preceded by the formation of a strong non-covalent complex. However, an up to 5-fold difference in inactivation rates among homologs hinted at structural or electrostatic differences
Epidemiological analysis of ozone and nitrogen impacts on vegetation - critical evaluation and recommendations (Publications)
model and conditions to be satisfied by the data; (4) selection of the relevant explanatory variables; (5) treatment of interactions and confounding factors; and (6) assessment of model validity.
