<em>Plasmodium vivax</em> antigen discovery based on alpha-helical coiled coil protein motif (Publications)
Protein alpha-helical coiled coil structures that elicit antibody responses, which block critical functions of medically important microorganisms, represent a means for vaccine development. By using b
Surveillance-response systems: the key to elimination of tropical diseases (Publications)
Tropical diseases remain a major cause of morbidity and mortality in developing countries. Although combined health efforts brought about significant improvements over the past 20 years, communities i
<em>Mycobacterium ulcerans</em> persistence at a village water source of Buruli ulcer patients (Publications)
Buruli ulcer (BU), a neglected tropical disease of the skin and subcutaneous tissue, is caused by Mycobacterium ulcerans and is the third most common mycobacterial disease after tuberculosis and lepro
Feasibility of repellent use in a context of increasing outdoor transmission: a qualitative study in rural Tanzania (Publications)
BACKGROUND: Extensive employment of long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) has substantially reduced malaria morbidity and mortality in sub-Saharan Africa. These too
Tuberculosis in antiretroviral treatment programs in lower income countries: availability and use of diagnostics and screening (Publications)
OBJECTIVES: In resource-constrained settings, tuberculosis (TB) is a common opportunistic infection and cause of death in HIV-infected persons. TB may be present at the start of antiretroviral therapy
Do topical repellents divert mosquitoes within a community? Health equity implications of topical repellents as a mosquito bite prevention tool (Publications)
OBJECTIVES: Repellents do not kill mosquitoes - they simply reduce human-vector contact. Thus it is possible that individuals who do not use repellents but dwell close to repellent users experience mo
Water, sanitation, hygiene, and soil-transmitted helminth infection: a systematic review and meta-analysis (Publications)
BACKGROUND: Preventive chemotherapy represents a powerful but short-term control strategy for soil-transmitted helminthiasis. Since humans are often re-infected rapidly, long-term solutions require im
Efficacy and safety of dihydroartemisinin-piperaquine for treatment of <em>Plasmodium vivax</em> malaria in endemic countries: meta-analysis of... (Publications)
BACKGROUND: This study aimed to synthesize available evidence on the efficacy of dihydroartemisinin-piperaquine (DHP) in treating uncomplicated Plasmodium vivax malaria in people living in endemic cou
Orally active antischistosomal early leads identified from the open access malaria box (Publications)
BACKGROUND: Worldwide hundreds of millions of schistosomiasis patients rely on treatment with a single drug, praziquantel. Therapeutic limitations and the threat of praziquantel resistance underline t
