Chemotherapy for major food-borne trematodes: a review (Publications)
Food-borne trematode infections, caused by liver flukes (Clonorchis, Fasciola, Opisthorchis), lung flukes (Paragonimus) and intestinal flukes (Echinostoma, Fasciolopsis, heterophyids), are significant
Effect of irrigated rice agriculture on Japanese encephalitis, including challenges and opportunities for integrated vector management (Publications)
Japanese encephalitis (JE) is a disease caused by an arbovirus that is spread by marsh birds, amplified by pigs, and mainly transmitted by the bite of infected Culex tritaeniorhynchus mosquitoes. The
Activity of artemether and mefloquine against juvenile and adult <em>Schistosoma mansoni</em> in athymic and immunocompetent NMRI mice (Publications)
Immune effector mechanisms can enhance the activity of antischistosomal drugs. We examined the in vivo effect of single oral doses of the antimalarials artemether (400 mg/kg) and mefloquine (200 mg/kg
Update on the diagnosis and treatment of food-borne trematode infections (Publications)
PURPOSE OF REVIEW: More than 40 million people are affected by food-borne trematode infections. Diagnosis is unsatisfactory and there are only two drugs available for treatment and control: praziquant
<em>Fasciola hepatica</em>: tegumental alterations in adult flukes following in vitro and in vivo administration of artesunate and artemether (Publications)
The tegumental changes in adult Fasciola hepatica induced by artemether and artesunate were assessed utilizing scanning electron microscopy (SEM). F hepatica were incubated with artemether and artesun
The role of parasitic infections in atopic diseases in rural schoolchildren (Publications)
BACKGROUND: There is increasing evidence that the farming environment has a protective effect as regards allergic diseases. Exposure to animal parasites, particularly helminth infections, is common in
Anthelmintic activity of artesunate against <em>Fasciola hepatica</em> in naturally infected sheep (Publications)
In light of rapidly spreading triclabendazole resistance alternative fasciocidal drugs are urgently needed. Following up on promising results obtained with artemether in Fasciola hepatica infected she
Effect of irrigation and large dams on the burden of malaria on a global and regional scale (Publications)
Human-made ecologic transformations have occurred at an unprecedented rate over the past 50 years. Prominent among them are water resource development projects. An estimated 40,000 large dams and 800,
<em>Plasmodium berghei</em> ANKA: selection of resistance to piperaquine and lumefantrine in a mouse model (Publications)
We have selected piperaquine (PQ) and lumefantrine (LM) resistant Plasmodium berghei ANKA parasite lines in mice by drug pressure. Effective doses that reduce parasitaemia by 90% (ED(90)) of PQ and LM
