Activity of antiandrogens against juvenile and adult <em>Schistosoma mansoni </em>in mice (Publications)
Objectives The antischistosomal properties of the marketed antiandrogens bicalutamide, flutamide, nilutamide and cyproterone acetate were studied both in vivo and in vitro. Methods Schistosoma mansoni
Anémie dans une école du Cambodge rural: détection, prévalence et liens avec les parasitoses intestinales et la malnutrition (Publications)
According to WHO, half of the world's children suffers from anaemia, which is a silent and neglected endemic resulting from three major causes: iron deficiency intestinal worms and malaria. A two mont
Efficacy and safety of mefloquine, artesunate, mefloquine-artesunate, and praziquantel against <em>Schistosoma haematobium</em>: randomized,... (Publications)
BACKGROUND: Morbidity control of schistosomiasis relies on a single drug, praziquantel. The antimalarial drug mefloquine possesses interesting antischistosomal properties, yet no clinical studies have
Isothermal microcalorimetry to study the activity of triclabendazole and its metabolites on juvenile and adult <em>Fasciola hepatica</em> (Publications)
Isothermal microcalorimetry (IMC) is an analytical tool that continuously measures the heat flow generated by chemical, physical or biological processes. We have demonstrated that IMC is a useful tool
Association between <em>Schistosoma mansoni </em>and hookworm infections among schoolchildren in Côte d'Ivoire (Publications)
Infections with Schistosoma mansoni and hookworms are widespread in sub-Saharan Africa and the burden of disease associated with both parasites is enormous. Although there is a large overlap in their
Malaria elimination: moving forward with spatial decision support systems (Publications)
Operational challenges facing contemporary malaria elimination have distinct geospatial elements including the need for high-resolution location-based surveillance, targeted prevention and response in
<em>In vivo</em> activity of aryl ozonides against <em>Schistosoma</em> species (Publications)
We evaluated the in vivo antischistosomal activities of 11 structurally diverse synthetic peroxides. Of all compounds tested, ozonide (1,2,4-trioxolane) OZ418 had the highest activity against adult Sc