Buruli ulcer disease: prospects for a vaccine (Publications)
Buruli ulcer disease (BUD), caused by Mycobacterium ulcerans, is a neglected bacterial infection of the poor in remote rural areas, mostly affecting children. BUD is a mutilating disease leading to se
Prevalence, motivations, and adverse effects of vaginal practices in Africa and Asia: findings from a multicountry household survey (Publications)
Abstract Background: Women worldwide use various vaginal practices to clean or modify their vulva and vagina. Additional population-level information is needed on prevalence and motivations for these
Lack of antigenic diversification of major outer membrane proteins during clonal waves of <em>Neisseria meningitidis</em> serogroup A colonization and... (Publications)
In particular in the 'meningitis belt' of sub-Saharan Africa, epidemic meningococcal meningitis is a severe public health problem. In the past decades, serogroup A lineages have been the dominant etio
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk (Publications)
Blood pressure is a heritable trait influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension (> /=140 mm Hg systolic blood
Antischistosomal activities of mefloquine-related arylmethanols (Publications)
Interesting antischistosomal properties have been documented for the antimalarial mefloquine, a 4-quinolinemethanol. We evaluated the antischistosomal activities of nine mefloquine related compounds,
Feeding and survival of the malaria vector Anopheles gambiae on plants growing in Kenya (Publications)
The propensity of the malaria vector mosquito Anopheles gambiae Giles (Diptera: Culicidae) to ingest sugars from various plants, and subsequent survival rates, were assessed with laboratory-reared mal
Decreased PM10 exposure attenuates age-related lung function decline: genetic variants in p53, p21, and CCND1 modify this effect (Publications)
BACKGROUND: Decreasing exposure to airborne particulates was previously associated with reduced age-related decline in lung function. However, whether the benefit from improved air quality depends on
A single LC-tandem mass spectrometry method for the simultaneous determination of 14 antimalarial drugs and their metabolites in human plasma (Publications)
Among the various determinants of treatment response, the achievement of sufficient blood levels is essential for curing malaria. For helping us at improving our current understanding of antimalarial
