Glutathione S-transferase genotype increases risk of progression from bronchial hyperresponsiveness to asthma in adults (Publications)
BACKGROUND: Bronchial hyperresponsiveness (BHR) and variation in glutathione S-transferase (GST) genes have been associated with asthma risk. The relationship of these two risk factors with adult onse
<em>Trypanothione reductase</em> high-throughput screening campaign identifies novel classes of inhibitors with anti-parasitic activity (Publications)
A high-throughput screening campaign of 100,000 lead like compounds led to the identification of 9 novel chemical classes of trypanothione reductase (TR) inhibitors worthy of further investigation. Hi
Optimization of chloronitrobenzamides (CNBs) as therapeutic leads for Human African Trypanosomiasis (HAT) (Publications)
We previously reported the discovery of the activity of chloronitrobenzamides (CNBs) against bloodstream forms of Trypanosoma brucei . Herein we disclose extensive structure-activity relationship and
Effectiveness of a comprehensive schistosomiasis japonica control program in Jiangsu province, China, from 2005 to 2008 (Publications)
The effectiveness of a comprehensive schistosomiasis japonica control program implemented in 8 villages along the Yangtze river in Jiangsu province from 2005 to 2008 was studied. Control measures incl